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Research

Explor: Exosome engineering for drug delivery

Writer : KAIST Date : 2017-09-22 Hit : 394 Email : jsoh33@kaist.ac.kr
Author : Chul Hee Choi Publication Date : 2016
Summary:
We have recently developed a novel extracellular vesicles–based protein carrier EXPLOR that can deliver therapeutic proteins efficiently in vitro and in vivo using active targeting induced by light stimulation. The technique allows an endogenous active protein loading process instead of exogenous passive loading, thus not only this technology eliminates the need for separation and purification of recombinant proteins, but also most of the intracellular proteins could be targets for EXPLOR-based therapeutics with high efficiency. We suggested EXPLOR will overcome the limitations of the previous protein drug delivery methods, opening a new paradigm for future biopharmaceuticals.
Publication text:

Explor: Exosome engineering for drug delivery 이미지1

KAIST, 291 Daehak-ro, Yuseong-gu, Daejeon 34141, Republic of Korea

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