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WORLD CLASS S&T UNIVERSITY

Academics

College of Life Science and Bioengineering

With the specialization of biology, brain science, medical science, and IT/NT, KAIST has accumulated academic capability in the area of biology. The College of Life Science and Bioengineering was founded to efficiently support the fusion research environment of KI for Biocentury at KAIST.

The College of Life Science and Bioengineering is composed of the Department of Biological Sciences, Department of Bio & Brain Engineering, and Graduate School of Medical Science & Engineering. The college pursues multidisciplinary education & research in the area of biology and the development of modern science through the fusion of the IT & NT foundation techniques for the development of the nation’s biological science and technology.

The Department of Biological Sciences fosters scientists and engineers of life science and biotechnology equipped with creative research skills to lead in the development of science and technology in the area of biological sciences and excellent scientists equipped with future oriented thinking and a holistic personality.

The multidisciplinary Department of Bio & Brain Engineering fosters a creative workforce that is capable of creating new knowledge and techniques in the fusion areas of electronics, computers, and nanotechnology based on biomedical science.

The Graduate School of Medical Science & Engineering is catered to doctors (specialists), graduates from medical schools, dental schools, and schools of oriental medicine for the development of new medicine and medical devices. The Graduate School of Medical Science & Engineering was established with the purpose of developing life sciences and medical technology and fostering a high-quality workforce equipped with a multidisciplinary knowledge in basic medicine, life science, and biomedical engineering, as well as research experience.

Academic Degree Curriculum
Academic Degree Curriculum
Department/Major Bachelor's Courses Master's Courses Doctoral Courses Office of Academic Affairs Website
Department of Biological Sciences
042-350-2602(F.2610) Homepage go
Graduate School of Medical Science and Engineering
  042-350-4232(F.4240) Homepage go
Interdisciplinary Majors and Educational Programs
Education Program
College
(Department/Major)
Interdisciplinary Majors and Educational Programs Bachelor's Courses Master's Courses Doctoral Courses Office of Academic Affairs Website
Graduate School of Medical Science and Engineering
Biomedical Science and Engineering
Interdisciplinary Program
  042-350-4232(F.4240) Homepage go
※ Department of Bio and Brain Engineering is changed of affiliation from College of Life Science and Bioengineering to College of Engineering on March 1st, 2015.
KAIST COMPASS in Life Science & Bioengineering
2018 Spring Dietary-mediated ROS generation in macrophage Paradigm shift in a classic neuroscience model Bystander Activation of T-Cells during Viral Infection Inducing of Neuron-Specific Nucleosome BAF53b upon Fear Learning Discovery of “crosstalk” towards the prevention of fatty liver development 2017 Fall Archeological traces of embryo development in adult Architecture of a gatekeeper translocating Structural determinations shed light on MDGA Overturning conventional thinking in Parkinson’s ATP-dependent chromatin remodeler Ino80 replaces
News
 
Flexible Drug Delivery Microdevice to Advance Precision Medicine


Schematic view of flexibe microdevice: The flexible drug delivery device for controlled release
(Figure 1. Schematic view of flexibe microdevice: The flexible drug delivery device for controlled release fabricated via inorganic laser lift off .)

A KAIST research team has developed a flexible drug delivery device with controlled release for personalized medicine, blazing the path toward theragnosis.


Theragnosis, an emerging medical technology, is gaining attention as key factor to advance precision medicine for its featuring simultaneous diagnosis and therapeutics. Theragnosis devices including smart contact lenses and microneedle patches integrate physiological data sensors and drug delivery devices. The controlled drug delivery boasts fewer side-effects, uniform therapeutic results, and minimal dosages compared to oral ingestion. Recently, some research groups conducted in-human applications of controlled-release bulky microchips for osteoporosis treatment.

However they failed to demonstrate successful human-friendly flexible drug delivery systems for controlled release.



For this microdevice, the team under Professor Daesoo Kim from the Department of Biological Science and Professor Keon Jae Lee from the Department of Materials Science and Engineering, fabricated a device on a rigid substrate and transferred a 50 µm-thick active drug delivery layer to the flexible substrate via inorganic laser lift off. The fabricated device shows mechanical flexibility while maintaining the capability of precise administration of exact dosages at desired times. The core technology is to produce a freestanding gold capping layer directly on top of the microreservoir with the drugs inside, which had been regarded as impossible in conventional microfabrication.

 

The developed flexible drug delivery system can be applied to smart contact lenses or the brain disease treatments by implanting them into cramped and corrugated organs. In addition, when powered wirelessly, it will represent a novel platform for personalized medicine. The team already proved through animal experimentation that treatment for brain epilepsy made progress by releasing anti-epileptic medication through the device.

Professor Lee believes the flexible microdevice will further expand the applications of smart contact lenses, therapeutic treatments for brain disease, and subcutaneous implantations for daily healthcare system. This study “Flexible Wireless Powered Drug Delivery System for Targeted Administration on Cerebral Cortex” was described in the June online issue of Nano Energy.

 

 


The flexible drug delivery device for contolled relase attached on a glass rod

Figure 2. The flexible drug delivery device for contolled relase attached on a glass rod.

Newsletter
Department of Biological Sciences KAIST COMPASS
Contact Information for the College of Life Science and Bioengineering: 042-350-ext.

Office of the Dean of the College of Life Science and Bioengineering: 2125
College of Life Science and Bioengineering Academic and Student Affairs Team: 1401, 1409, Fax: 1400

KAIST, 291 Daehak-ro, Yuseong-gu, Daejeon 34141, Republic of Korea

T. 042-350-2114 / F. 042-350-2210 (2220)

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