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Distinguished Professor Sang Yup Lee Named NAI Fellow
(Distinguished Professor Sang Yup Lee)
Distinguished Professor Sang Yup Lee of the Department of Chemical and Biomolecular Engineering was named to the National Academy of Inventors in the US. He is the first Korean scholar ever elected as a NAI fellow.
The NAI is a non-profit member organization with over 4,000 individual inventors and fellows spanning more than 250 institutions worldwide. It is comprised of universities as well as governmental and non-profit research institutes. The academy was founded in 2010 to recognize and encourage inventors with patents from the US Patent and Trademark Office. So far, 575 fellows from 229 institutions have been elected.
The academy said Professor Lee has been recognized for fellowship induction as he has demonstrated a highly prolific spirit of innovation in creating or facilitating outstanding inventions that have made a tangible impact on quality of life, economic development, and the welfare of society.
Distinguished Professor Lee, a pioneering researcher and scholar in the field of systems metabolic engineering, was ranked in the top 1% of highly cited researchers (HCR) this year. Over the past 11 years, he published more than 130,000 articles in prestigious journals around the world. He has been cited more than 34,000 times since he started working at KAIST in 1994.
He is also the first Korean ever elected to both the National Academy of Sciences (NAS) and the National Academy of Engineering (NAE) in the US, becoming the one of 13 foreign scholars in the world holding two prestigious institutions’ fellowships.
Dr. Lee is currently the dean of KAIST Institutes, the world-leading institute for multi and interdisciplinary research. He is also serving as co-chair of the Global Council on Biotechnology and is a member of the Global Future Council on the Fourth Industrial Revolution at the World Economic Forum.
2017.12.13 View 10518 -
Highly Sensitive and Fast Indoor GNSS Signal Acquisition Technology
(Professor Seung-Hyun Kong (right) and Research Fellow Tae-Sun Kim)
A research team led by Professor Seung-Hyun Kong at the Cho Chun Shik Graduate School of Green Transportation, KAIST, developed high-speed, high-sensitivity Global Navigation Satellite System (GNSS) signal acquisition (search and detection) technology that can produce GNSS positioning fixes indoors.
Using the team’s new technology, GNSS signals will be sufficient to identify locations anywhere in the world, both indoors and outdoors. This new research finding was published in the international journal IEEE Signal Processing Magazine (IEEE SPM) this September.
Global Positioning System (GPS) developed by the U.S. Department of Defense in the 1990s is the most widely-used satellite-based navigation system, and GNSS is a terminology to indicate conventional satellite based navigation systems, such as GPS and Russian GLONASS, as well as new satellite-based navigation systems under development, such as European GALILEO, Chinese COMPASS, and other regional satellite-based navigation systems.
In general, GNSS signals are transmitted all over the globe from 20,000 km above the Earth and thus a GNSS signal received by a small antennae in an outdoor environment has weak signal power. In addition, GNSS signals penetrating building walls become extremely weak so the signal can be less than 1/1000th of the signal power received outside.
Using conventional acquisition techniques including the frequency-domain correlation technique to acquire an extremely weak GNSS signal causes the computational cost to increase by over a million times and the processing time for acquisition also increases tremendously. Because of this, indoor measurement techniques using GNSS signals were considered practically impossible for the last 20 years.
To resolve such limitations, the research team developed a Synthesized Doppler-frequency Hypothesis Testing (SDHT) technique to dramatically reduce the acquisition time and computational load for extremely weak GNSS signals indoors.
In general, GNSS signal acquisition is a search process in which the instantaneous accurate code phase and Doppler frequency of the incoming GNSS signal are identified. However, the number of Doppler frequency hypotheses grows proportionally to the coherent correlation time that should be necessarily increased to detect weak signals. In practice, the coherent correlation time should be more than 1000 times longer for extremely weak GNSS signals so the number of Doppler frequency hypotheses is greater than 20,000. On the other hand, the SDHT algorithm indirectly tests the Doppler frequency hypothesis utilizing the coherent correlation results of neighboring hypotheses.
Therefore, using SDHT, only around 20 hypotheses are tested using conventional correlation techniques and the remaining 19,980 hypotheses are calculated with simple mathematical operations. As a result, SDHT achieves a huge computational cost reduction (by about 1000 times) and is 800 times faster for signal acquisition compared to conventional techniques. This means only about 15 seconds is required to detect extremely weak GNSS signals in buildings using a personal computer.
The team predicts further studies for strengthening SDHT technology and developing positioning systems robust enough to multipath in indoor environments will allow indoor GNSS measurements within several seconds inside most buildings using GNSS alone.
Professor Kong said, “This development made us the leader in indoor GNSS positioning technology in the world.” He continued, “We hope to commercialize indoor GNSS systems to create a new market.” The research team is currently registering a patent in Korea and applying for patents overseas, as well as planning to commercialize the technology with the help of the Institute for Startup KAIST.
(Figure1. Positioning Results for the GPS Indoor Positioning System using SDHT Technology)
2017.11.02 View 7878 -
Humicotta Wins the Silver Prize at the 2017 IDEA
The 3D-printed ceramic humidifier made by the research team led by Professor Sang-Min Bae won the silver prize at the 2017 International Design Excellence Awards (IDEA). Professor Bae’s ID+IM team was also listed as winners of three more appropriate technology designs at the IDEA. The awards, sponsored by the Industrial Designers Society of America, are one of the three prestigious design awards including the Red Dot Design Award and the iF Design Award in Germany.
The silver prize winner in the category of home and bath, Humicotta is an energy-efficient, bacteria free, and easy to clean humidifier. It includes a base module and filter. The base is a cylindrical pedestal with a built-in fan on which the filter is placed. The filter is a 3D-printed honeycomb structure made of diatomite. When water is added, the honeycomb structure and porous terracotta maximize natural humidification. It also offers an open platform service that customizes the filters or provides files that users can use their own 3D printer.
Professor Bae’s team has worked on philanthropy design using appropriate technology as their main topic for years. Their designs have been recognized at prestigious global design awards events, winning more than 50 prizes with innovative designs made for addressing various global and social problems.
The Light Funnel is a novel type of lighting device designed for off-grid areas of Africa. It helps to maximize the natural light effect in the daytime without any drastic home renovations. It consists of a transparent acrylic sphere and a reflective pathway. After filling the acrylic sphere with water and placing it on a rooftop, sunlight passes into the house through the water inside the sphere. It provides a lighted environment nine times brighter than without it. Also, once installed, it can be used almost permanently.
The Maasai Smart Cane is made using wood sticks purchased through fair trade with the Maasai tribe. GPS is installed into the grip of the birch-tree cane, so that cane users can send a signal when in an emergency situation. All of the proceeds of this product go to the tribe.
S.Cone is a first aid kit made in collaboration with Samsung Fire and Marine Insurance. The traffic cone-shaped kit is designed to help users handle an emergency situation intact and safe. The S.Cone has unique versions for fires, car accidents, and marine accidents. For example, the S.Cone for fires is equipped with a small fire extinguisher, smoke mask, and fire blanket. The cap of the S.Cone also functions as an IoT station connecting the fire and gas detector with smart phones.
Professor Bae said of his team’s winning design products, “By making the data public, any person can design their own humidifier if they have access to a 3D-printer. We want it to be a very accessible product for the public. The Light Funnel and Maasai Smart Cane are designed for economically-marginalized populations and the elderly. We will continue to make the best designed products serving the marginalized 90% of the population around the world.”
2017.09.14 View 29846 -
KAIST Professors Sweep the Best Science and Technology Award
(Distinguished Professors Sang Yup Lee (left) and Kyu-Young Whang)
Distinguished Professors Sang Yup Lee from the Department of Chemical and Biomolecular Engineering and Kyu-Young Whang of the College of Computing were selected as the winners of the "2017 Korea Best Science and Technology Award" by the Ministry of Science, ICT and Future Planning (MSIP) and the Korea Federation of Science and Technology Societies.
The award, which was established in 2003, is the highest honor bestowed to the two most outstanding scientists in Korea annually. This is the first time that KAIST faculty members have swept the award since its founding.
Distinguished Professor Lee is renowned for his pioneering studies of system metabolic engineering, which produces useful chemicals by utilizing microorganisms. Professor Lee has developed a number of globally-recognized original technologies such as gasoline production using micro-organisms, a bio-butanol production process, microbes for producing nylon and plastic raw materials, and making native-like spider silk produced in metabolically engineering bacterium which is stronger than steel but finer than human hair.
System metabolism engineering was also selected as one of the top 10 promising technologies in the world in 2016 by the World Economic Forum. Selected as one of the world’s top 20 applied bioscientists in 2014 by Nature Biotechnology, he has many ‘first’ titles in his academic and research careers. He was the first Asian to win the James Bailey Award (2016) and Marvin Johnson Award (2012), the first Korean elected to both the US National Academy of Science (NAS) and the National Academy of Engineering (NAE) this year. He is the dean of KAIST institutes, a multi and interdisciplinary research institute at KAIST. He serves as co-chair of the Global Council on Biotechnology and as a member of the Global Future Council on the Fourth Industrial Revolution at the World Economic Forum.
Distinguished Professor Whang, the first recipient in the field of computer science in this award, has been recognized for his lifetime achievement and contributions to the development of the software industry and the spreading of information culture. He has taken a pioneering role in presenting novel theories and innovative technologies in the field of database systems such as probabilistic aggregation, multidimensional indexing, query, and database and information retrieval. The Odysseus database management system Professor Hwang developed has been applied in many diverse fields of industry, while promoting the domestic software industry and its technical independence.
Professor Hwang is a fellow at the American Computer Society (ACM) and life fellow at IEEE. Professor Whang received the ACM SIGMOD Contributions Award in 2014 for his work promoting database research worldwide, the PAKDD Distinguished Contributions Award in 2014, and the DASFAA Outstanding Contributions Award in 2011 for his contributions to database and data mining research in the Asia-Pacific region. He is also the recipient of the prestigious Korea (presidential) Engineering Award in 2012.
2017.07.03 View 13349 -
Distinguished Professor Lee Elected to the NAS
Distinguished Professor Sang Yup Lee of the Department of Chemical and Biomolecular Engineering was elected as a foreign associate to the US National Academy of Sciences (NAS) on May 2. The National Academy of Sciences elected 84 new members and 21 foreign associates in recognition of their distinguished and continuing achievements in their original research. Election to the Academy is widely regarded as one of the highest honors that a scientist can receive.
Professor Lee was also elected in 2010 as a member of the US National Academy of Engineering (NAE) for his leadership in microbial biotechnology and metabolic engineering, including the development of fermentation processes for biodegradable polymers and organic acids. Until 2016, there are only 12 people worldwide who are foreign associates of both NAS and NAE.
He is the first Korean elected to both prestigious academies, the NAS and the NAE in the US. Professor Lee is currently the dean of KAIST Institutes, the world leading institute for multi-and interdisciplinary research. He is also serving as co-chair of the Global Council on Biotechnology and member of the Global Future Council on the Fourth Industrial Revolution, the World Economic Forum.
2017.05.16 View 11854 -
Unveiling the Distinctive Features of Industrial Microorganism
KAIST researchers have sequenced the whole genome of Clostridium tyrobutyricum, which has a higher tolerance to toxic chemicals, such as 1-butanol, compared to other clostridial bacterial strains.
Clostridium tyrobutyricum, a Gram-positive, anaerobic spore-forming bacterium, is considered a promising industrial host strain for the production of various chemicals including butyric acid which has many applications in different industries such as a precursor to biofuels. Despite such potential, C. tyrobutyricum has received little attention, mainly due to a limited understanding of its genotypic and metabolic characteristics at the genome level.
A Korean research team headed by Distinguished Professor Sang Yup Lee of the Chemical and Biomolecular Engineering Department at the Korea Advanced Institute of Science and Technology (KAIST) deciphered the genome sequence of C. tyrobutyricum and its proteome profiles during the course of batch fermentation. As a result, the research team learned that the bacterium is not only capable of producing a large amount of butyric acid but also can tolerate toxic compounds such as 1-butanol. The research results were published in mBio on June 14, 2016.
The team adopted a genoproteomic approach, combining genomics and proteomics, to investigate the metabolic features of C. tyrobutyricum. Unlike Clostridium acetobutylicum, the most widely used organism for 1-butanol production, C. tyrobutyricum has a novel butyrate-producing pathway and various mechanisms for energy conservation under anaerobic conditions. The expression of various metabolic genes, including those involved in butyrate formation, was analyzed using the “shotgun” proteome approach.
To date, the bio-based production of 1-butanol, a next-generation biofuel, has relied on several clostridial hosts including C. acetobutylicum and C. beijerinckii. However, these organisms have a low tolerance against 1-butanol even though they are naturally capable of producing it. C. tyrobutyricum cannot produce 1-butanol itself, but has a higher 1-butanol-tolerance and rapid uptake of monosaccharides, compared to those two species.
The team identified most of the genes involved in the central metabolism of C. tyrobutyricum from the whole-genome and shotgun proteome data, and this study will accelerate the bacterium’s engineering to produce useful chemicals including butyric acid and 1-butanol, replacing traditional bacterial hosts.
Professor Lee said,
“The unique metabolic features and energy conservation mechanisms of C. tyrobutyricum can be employed in the various microbial hosts we have previously developed to further improve their productivity and yield. Moreover, findings on C. tyrobutyricum revealed by this study will be the first step to directly engineer this bacterium.”
Director Jin-Woo Kim at the Platform Technology Division of the Ministry of Science, ICT and Future Planning of Korea, who oversees the Technology Development Program to Solve Climate Change, said,
“Over the years, Professor Lee’s team has researched the development of a bio-refinery system to produce natural and non-natural chemicals with the systems metabolic engineering of microorganisms. They were able to design strategies for the development of diverse industrial microbial strains to produce useful chemicals from inedible biomass-based carbon dioxide fixation. We believe the efficient production of butyric acid using a metabolic engineering approach will play an important role in the establishment of a bioprocess for chemical production.”
The title of the research paper is “Deciphering Clostridium tyrobutyricum Metabolism Based on the Who-Genome Sequence and Proteome Analyses.” (DOI: 10.1128/mBio.00743-16)
The lead authors are Joungmin Lee, a post-doctoral fellow in the BioProcess Research Center at KAIST, currently working in CJ CheilJedang Research Institute; Yu-Sin Jang, a research fellow in the BioProcess Research Center at KAIST, currently working at Gyeongsang National University as an assistant professor; and Mee-Jung Han, an assistant professor in the Environmental Engineering and Energy Department at Dongyang University. Jin Young Kim, a senior researcher at the Korea Basic Science Institute, also participated in the research.
This research was supported by the Technology Development Program to Solve Climate Change’s research project entitled “Systems Metabolic Engineering for Biorefineries” from the Ministry of Science, ICT and Future Planning through the National Research Foundation of Korea (NRF-2012M1A2A2026556).
Schematic Diagram of C. tyrobutyricum’s Genome Sequence and Its Proteome Profiles
The picture below shows the complete genome sequence, global protein expression profiles, and the genome-based metabolic characteristics during batch fermentation of C. tyrobutyricum.
2016.06.20 View 12082 -
Professor Naehyuck Chang Appointed a 2015 Fellow by the ACM
The Association for Computing Machinery (ACM), the world’s largest educational and scientific computing society, released a list of its new fellows on December 8, 2015, the 2015 ACM Fellows.
Professor Naehyuck Chang of the School of Electrical Engineering at KAIST was among the 42 new members who became ACM Fellows in recognition of their contributions to the development and application of computing in areas from data management and spoken-language processing to robotics and cryptography.
Professor Chang is known for his leading research in power and energy optimization from embedded systems applications to large-scale energy systems such as device- and system-level power and energy measurement and estimation, liquid crystal display power reduction, dynamic voltage scaling, hybrid electrical energy storage systems, and photovoltaic cell arrays. He is the fourth Korean to be nominated an ACM Fellow.
Professor Chang is also a Fellow of the Institute of Electrical and Electronics Engineers (IEEE) and the Editor-in-Chief of the journal, ACM Transactions on Design Automation of Electronic Systems (TODAES). He served as the President of the ACM Special Interest Group on Design Automation in 2012.
Additional information about the ACM 2015 Fellows, go to http://www.acm.org/press-room/news-releases/2015/fellows-2015:
2015.12.11 View 10769 -
Professor Naehyuck Jang was Appointed Technical Program Chair of the Design Automation Conference
Professor Naehyuck Jang of the Electrical Engineering Department at KAIST was appointed as the technical program chair of the Design Automation Conference (DAC). He is the first Asian to serve the conference as the chair. At next year’s conference, he will select 150 program committee members and supervise the selection process of 1,000 papers.
Founded in 1964, DAC encompasses research related to automation of semiconductor processes, which usually involve billions of transistors. More than seven thousand people and 150 companies from all around the world participate, of which only the top 20% of the submitted papers are selected. It is the most prestigious conference in the field of semiconductor automation.
The Design Automation Conference also introduces optimization and automation of design processes of systems, hardware security, automobiles, and the Internet of things. Professor Jang specializes in low power system designs. As an ACM Distinguished Scientist, Professor Jang was elected as the chairman after contributing to this year’s program committee by reforming the process of selection of papers.
Professor Jang said, “This year’s conference represents a departure, where we move from the field of traditional semiconductors to the optimization of embedded system, the Internet of things, and security. He added that “we want to create a paper selection process that can propose the future of design automation.”
The 53rd annual DAC will take place at the Austin Convention Center in Texas in June 2016.
2015.07.02 View 8536 -
KAIST Robotic Art: Exhibit called "Artificial Brain, Robots Evolve"
It is not difficult to find the desire to create a Neoanthropinae in the history of mankind. Humans evolve through man-made extensions and live by self-training them. This is Seung Hyun Son’s description which encourages us to discuss the changes man-made humanoids would bring to our future lives. He depicts this in “Theory of Evolution: From mankind to humanoid” in the “Artificial Brain, Robots Evolve” exhibition in the KI Building, KAIST, from 21 November 2014 to 8 February 2015.
KAIST's Art and Design Committee (led by President Myung Seok Kim) is holding the third experimental art exhibition based on the integration of science and art. The previous exhibition themes were “See the Sky” in 2012 and “Life is Beautiful” in 2013. The exhibition is divided into five subtopics: Move, Feel, Think, Express, and Experiment in Imagination.
The exhibits are by 17 artists including Nam June Paik, Nancy Lang, and KAIST Professor Myung Seok Kim. The main exhibits include “Cloud Face,” by Seung Baek Shin and Yong Hoon Kim, that shows up as error on computer but can be seen by human eyes and “Brains in Vat," by Boo Rok Lee and Myung Chul Kim based on KAIST's robotic lab’s materials and motif. Also, “The May of My Life” by Professor Myung Seok Kim’s lab reminds us of the relationship between robot and human.
President Myung Seok Kim said, “The range of content in cultural art will inspire students’ imagination.” He continued, “I hope this exhibition will awaken both scientific ideas and artistic sense.”
The opening ceremony of the exhibition will be held from 14:00, 21 November. The “Artificial Brain, Robots Evolve” exhibition is hosted by the Daejeon Museum of Art and sponsored by National Museum of Modern and Contemporary Art and Soma Museum.
Pictures from top to bottom are Cloud Face, Brains in Vat, The May of My Life_1, and The May of My Life_2.
2014.11.21 View 9102 -
Students Meet with KAIST Development Foundation
A group of department representatives and distinguished school staff gathered on November 21st to discuss the future funding of Korea Advanced Institute of Science and Technology (KAIST). Participants of the meeting included the Vice President, Dean of Academic Affairs, Director of Welfare, the President of Undergraduate Student Association, and many more. The Vice President explained that students and alumnae are the owners of KAIST and should take pride in the successful development of KAIST. He also added that they should share the same goal of supporting KAIST to become the world"s leading institute of science and technology.
Statistics show a noticeable correlation between a university"s status in world rankings and the percentage of its alumni donation participants. In the case of top U.S. universities, a large number of their alumnae donate astronomical sums of money in hopes to contribute to the school"s development. For example, in 2006, a whopping 61% of the Princeton University alumni participated in school donations, while - in stark contrast - a meager 1.1% of 31,000 KAIST alumnae made monetary contributions. Perhaps this low level of donation participation explains why KAIST is making little progress in its efforts to advance into a globally-recognized university.
"Before we die, many of us look back and regret "I should"ve earned a little more"," said the Vice President. "But what we should really reflect on is how I could"ve given a little more." Throughout the meeting, he reiterated the significance of enrolled students practicing donation, no matter how insignificant the amount, when they are still young.
KAIST is currently receiving support from its alumni, parents, students, corporations, foundations, professors and staff. With a growing demand for increasing the number of professors, research fees and labor budget, however, KAIST requires the full support and dedication of students and alumnae alike if it is to fulfill its vision of becoming the academic leader in science and technology- it is essential for students to get accustomed to the habit of donating to the school. To promote this practice of contributing, the Vice President urged students to look for opportunities to make donations.By KAIST Herald on December, 2007
2007.12.21 View 15382