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PICASSO Technique Drives Biological Molecules into Technicolor
The new imaging approach brings current imaging colors from four to more than 15 for mapping overlapping proteins Pablo Picasso’s surreal cubist artistic style shifted common features into unrecognizable scenes, but a new imaging approach bearing his namesake may elucidate the most complicated subject: the brain. Employing artificial intelligence to clarify spectral color blending of tiny molecules used to stain specific proteins and other items of research interest, the PICASSO technique, allows researchers to use more than 15 colors to image and parse our overlapping proteins. The PICASSO developers, based in Korea, published their approach on May 5 in Nature Communications. Fluorophores — the staining molecules — emit specific colors when excited by a light, but if more than four fluorophores are used, their emitted colors overlap and blend. Researchers previously developed techniques to correct this spectral overlap by precisely defining the matrix of mixed and unmixed images. This measurement depends on reference spectra, found by identifying clear images of only one fluorophore-stained specimen or of multiple, identically prepared specimens that only contain a single fluorophore each. “Such reference spectra measurement could be complicated to perform in highly heterogeneous specimens, such as the brain, due to the highly varied emission spectra of fluorophores depending on the subregions from which the spectra were measured,” said co-corresponding author Young-Gyu Yoon, professor in the School of Electrical Engineering at KAIST. He explained that the subregions would each need their own spectra reference measurements, making for an inefficient, time-consuming process. “To address this problem, we developed an approach that does not require reference spectra measurements.” The approach is the “Process of ultra-multiplexed Imaging of biomolecules viA the unmixing of the Signals of Spectrally Overlapping fluorophores,” also known as PICASSO. Ultra-multiplexed imaging refers to visualizing the numerous individual components of a unit. Like a cinema multiplex in which each theater plays a different movie, each protein in a cell has a different role. By staining with fluorophores, researchers can begin to understand those roles. “We devised a strategy based on information theory; unmixing is performed by iteratively minimizing the mutual information between mixed images,” said co-corresponding author Jae-Byum Chang, professor in the Department of Materials Science and Engineering, KAIST. “This allows us to get away with the assumption that the spatial distribution of different proteins is mutually exclusive and enables accurate information unmixing.” To demonstrate PICASSO’s capabilities, the researchers applied the technique to imaging a mouse brain. With a single round of staining, they performed 15-color multiplexed imaging of a mouse brain. Although small, mouse brains are still complex, multifaceted organs that can take significant resources to map. According to the researchers, PICASSO can improve the capabilities of other imaging techniques and allow for the use of even more fluorophore colors. Using one such imaging technique in combination with PICASSO, the team achieved 45-color multiplexed imaging of the mouse brain in only three staining and imaging cycles, according to Yoon. “PICASSO is a versatile tool for the multiplexed biomolecule imaging of cultured cells, tissue slices and clinical specimens,” Chang said. “We anticipate that PICASSO will be useful for a broad range of applications for which biomolecules’ spatial information is important. One such application the tool would be useful for is revealing the cellular heterogeneities of tumor microenvironments, especially the heterogeneous populations of immune cells, which are closely related to cancer prognoses and the efficacy of cancer therapies.” The Samsung Research Funding & Incubation Center for Future Technology supported this work. Spectral imaging was performed at the Korea Basic Science Institute Western Seoul Center. -PublicationJunyoung Seo, Yeonbo Sim, Jeewon Kim, Hyunwoo Kim, In Cho, Hoyeon Nam, Yong-Gyu Yoon, Jae-Byum Chang, “PICASSO allows ultra-multiplexed fluorescence imaging of spatiallyoverlapping proteins without reference spectra measurements,” May 5, Nature Communications (doi.org/10.1038/s41467-022-30168-z) -ProfileProfessor Jae-Byum ChangDepartment of Materials Science and EngineeringCollege of EngineeringKAIST Professor Young-Gyu YoonSchool of Electrical EngineeringCollege of EngineeringKAIST
2022.06.22
View 9715
Team KAIST Makes Its Presence Felt in the Self-Driving Tech Industry
Team KAIST finishes 4th at the inaugural CES Autonomous Racing Competition Team KAIST led by Professor Hyunchul Shim and Unmanned Systems Research Group (USRG) placed fourth in an autonomous race car competition in Las Vegas last week, making its presence felt in the self-driving automotive tech industry. Team KAIST, beat its first competitor, Auburn University, with speeds of up to 131 mph at the Autonomous Challenge at CES held at the Las Vegas Motor Speedway. However, the team failed to advance to the final round when it lost to PoliMOVE, comprised of the Polytechnic University of Milan and the University of Alabama, the final winner of the $150,000 USD race. A total of eight teams competed in the self-driving race. The race was conducted as a single elimination tournament consisting of multiple rounds of matches. Two cars took turns playing the role of defender and attacker, and each car attempted to outpace the other until one of them was unable to complete the mission. Each team designed the algorithm to control its racecar, the Dallara-built AV-21, which can reach a speed of up to 173 mph, and make it safely drive around the track at high speeds without crashing into the other. The event is the CES version of the Indy Autonomous Challenge, a competition that took place for the first time in October last year to encourage university students from around the world to develop complicated software for autonomous driving and advance relevant technologies. Team KAIST placed 4th at the Indy Autonomous Challenge, which qualified it to participate in this race. “The technical level of the CES race is much higher than last October’s and we had a very tough race. We advanced to the semifinals for two consecutive races. I think our autonomous vehicle technology is proving itself to the world,” said Professor Shim. Professor Shim’s research group has been working on the development of autonomous aerial and ground vehicles for the past 12 years. A self-driving car developed by the lab was certified by the South Korean government to run on public roads. The vehicle the team used cost more than 1 million USD to build. Many of the other teams had to repair their vehicle more than once due to accidents and had to spend a lot on repairs. “We are the only one who did not have any accidents, and this is a testament to our technological prowess,” said Professor Shim. He said the financial funding to purchase pricy parts and equipment for the racecar is always a challenge given the very tight research budget and absence of corporate sponsorships. However, Professor Shim and his research group plan to participate in the next race in September and in the 2023 CES race. “I think we need more systemic and proactive research and support systems to earn better results but there is nothing better than the group of passionate students who are taking part in this project with us,” Shim added.
2022.01.12
View 10479
Mobile Clinic Module Wins Red Dot and iF Design Awards
The Mobile Clinic Module (MCM), an inflatable negative pressure ward building system developed by the Korea Aid for Respiratory Epidemic (KARE) initiative at KAIST, gained international acclaim by winning the prestigious Red Dot Design Award and iF Design Award. The MCM was recognized as one of the Red Dot Product Designs of the Year. It also won four iF Design Awards in communication design, interior architecture, user interface, and user experience. Winning the two most influential design awards demonstrates how product design can make a valuable contribution to help contain pandemics and reflects new consumer trends for dealing with pandemics. Designed to be patient friendly, even in the extreme medical situations such as pandemics or triage, the MCM is the result of collaborations among researchers in a variety of fields including mechanical engineering, computing, industrial and systems engineering, medical hospitals, and engineering companies. The research team was led by Professor Tek-Jin Nam from the Department of Industrial Design. The MCM is expandable, moveable, and easy to store through a combination of negative pressure frames, air tents, and multi-functional panels. Positive air pressure devices supply fresh air from outside the tent. An air pump and controller maintain air beam pressure, while filtering exhausted air from inside. An internal air information monitoring system efficiently controls inside air pressure and purifies the air. It requires only one-fourth of the volume of existing wards and takes up approximately 40% of their weight. The unit can be transported in a 40-foot container truck. MCMs are now located at the Korea Institute of Radiological & Medical Sciences and Jeju Vaccine Center and expect to be used at many other facilities. KARE is developing antiviral solutions and devices such as protective gear, sterilizers, and test kits to promptly respond to the pandemic. More than 100 researchers at KAIST are collaborating with industry and clinical hospitals to develop antiviral technologies that will improve preventive measures, diagnoses, and treatments. Professor Nam said, “Our designers will continue to identify the most challenging issues, and try to resolve them by realizing user-friendly functions. We believe this will significantly contribute to relieving the drastic need for negative pressure beds and provide a place for monitoring patients with moderate symptoms. We look forward to the MCM upgrading epidemic management resources around the globe.” (END)
2021.04.21
View 9850
KAIST International Symposium Highlights the Value of Science through Global Collaboration
The presidents of three premier science and technology universities shared their belief that universities should move forward to embrace social changes while maintaining the importance of academics for future generations during the KAIST International Symposium on February 16. The symposium, one of the events to celebrate KAIST’s 50th anniversary, highlighted the future role of universities over the next 50 years by hosting a panel featuring ETH Zurich President Joël Mesot, Caltech President Thomas Rosenbaum, and KAIST President Sung-Chul Shin. Members of the foreign diplomatic corps representing seven countries also explored the new model of global collaboration in the second session. President Rosenbaum of Caltech said that even though society is changing, the role of universities will not be different since the value of knowledge will always be important. He said that universities must embrace change. He said that universities should move forward fearlessly if they believe it would impact wider society positively. He added that universities should also be courageous enough to take a new path based on longer-term perspectives and lessons learned from successes. One of the roles of universities is to establish various hypotheses and possible prospects, raise doubts, and go forward with a strong will for the future generations to come. He cited LIGO (the Laser Inerferometer Gravitational-wave Observatory), as a good example of a successful university-research collaboration. LIGO is funded by the National Science Foundation in the US and operated by Caltech and MIT. Approximately 1300 scientists from around the world, including the Max Planck Society in Germany and the Science and Technology Facilities Council in the UK, participate in the LIGO Scientific Collaboration. In 2019, the international team of scientists detected the collision of two black holes with masses about 142 times the mass of the sun in the most massive collision ever detected. MIT Physicist Rainer Weiss shared the Nobel Prize in Physics with Professor Barry Barish and Professor Kip Thorn from the Department of Physics at Caltech in recognition of their contribution to the LIGO detector and the observation of gravitational waves. President Mesot of ETH Zurich stressed that universities should foster young talents well versed with creative thinking and entrepreneurship in this new era. He also said that COVID-19 has reaffirmed the importance of science and global collaborations beyond borders to address global challenges such as pandemics. President Mesot said COVID-19 has taught us the value of science and R&D, adding that the roll-out of a vaccine in only one year would have been impossible without the decades-long R&D foundation that universities and industries have established. He also gave the example of the MRI as a reason universities should provide strong basic science research foundation. In 1944 in the US, Dr. Isidor Isaac Rabi won the Nobel Prize in Physics for his discovery of nuclear magnetic resonance. The MRI research inspired many ETH professors for further studies and led them to win the Nobel Prize in Physics in 1952 for their MRI basic theory and in 1991 the Nobel Prize in Chemistry with the development of high-resolution spectroscopy. “The MRI first started 80 years ago and still applies in today’s medicine. We should focus on research which will keep such value,” President Mesot said. Meanwhile President Shin also said that the age of the Fourth Industrial Revolution has been deemed the "winner takes all" era. At this highly competitive time, R&D activities are more meaningful if they produce the world’s best, first, and only outcomes. “We aim to achieve excellence in research with long-term innovative research support systems. We will conduct R&D activities that will lead the megatrends of the Fourth Industrial Revolution: hyper-connectivity, super-intelligence, and meta-convergence. In addition, we will double down to conduct forward-looking flagship research that will enhance the happiness and prosperity of all humanity in the areas of global warming, infectious diseases, bio-medicine, energy and environment, smart technology, and post-AI.” Responding to one of the student’s question about what mindsets are expected of students enrolled in government-funded national universities, President Mesot made three suggestions. First, they should remember that they are privileged, so they should give back their talents to society. They should also be patient with what they are doing even when they don’t achieve the desired results. Lastly, they should remain open to new ideas and be flexible when encountering disruptions. Seven diplomats stationing in Korea including Rob Rapson, US Charge d’Affairs ad Interim Rob Rapson, UAE Ambassador Abdulla Saif Al Nuaimi, Kenyan Ambassador Mwende Mwinzi, Danish Ambassador Einar Jensen, Pakistani Ambassador Mumtaz Zahar Baloch, Egyptian Ambassador Haem Fahmy, and UK Ambassador Simon Smith joined the second session themed KAIST for the Global Community. They all agreed that KAIST is one of the shining examples of successful international collaboration stemming from the international aid loan from USAID. Five decades later, KAIST now is working to help the Kenyan government to establish Kenya KAIST with a 95-million US funding from the Korea Exim Bank. While stressing the importance of global collaboration for inclusive growth in the global community, the seven diplomats gave their insights on the newly transforming global environment intertwined with COVID-19 and the Fourth Industrial Revolution. In the face of global changes caused by emerging technologies and carbon neutrality, the ambassadors expressed a strong desire to make collaborations between KAIST and their countries to propel new innovations in industry and education in their countries.
2021.02.17
View 8979
KAIST Mobile Clinic Module to Fill Negative Pressure Ward Shortage
Efficient versatile ready-for-rapid building system of MCM will serve as both a triage unit and bridge center in emergency medical situations A team from KAIST has developed a low-cost and ready-for-rapid-production negative pressure room called a Mobile Clinic Module (MCM). The MCM is expandable, moveable, and easy to store through a combination of negative pressure frames, air tents, and multi-function panels. The MCM expects to quickly meet the high demand for negative pressure beds in the nation and eventually many other countries where the third wave of COVID-19 is raging. The module is now ready to be rolled out after a three-week test period at the Korea Cancer Center Hospital. Professor Tek-Jin Nam’s team swung into action, rapidly working together with researchers, engineers with expertise in mechanical design, and a team of clinical doctors to complete the MCM as one of KAIST’s New Deal R&D initiatives launched last July. Professor Nam cites ‘expandability’ as the key feature of the MCM. Eventually, it will serve as both a triage unit and bridge center in emergency medical situations. “The module is a very efficient and versatile unit building system. It takes approximately two hours to build the basic MCM unit, which comprises four negative pressure bed rooms, nurse’s station, locker room, and treatment room. We believe this will significantly contribute to relieving the drastic need for negative pressure beds and provide a place for monitoring patients with moderate symptoms,” said Professor Nam. “It will also be helpful for managing less-severe patients who need to be monitored daily in quarantined rooms or as bridge stations where on-site medical staff can provide treatment and daily monitoring before hospitalization. These wards can be efficiently deployed either inside or outside existing hospitals.” The research team specially designed the negative pressure frame to ensure safety level A for the negative pressure room, which is made of a multi-function panel wall and roofed with an air tent. The multi-function panels can hold medical appliances such as ventilators, oxygen and bio-signal monitors. Positive air pressure devices supply fresh air from outside the tent. An air pump and controller maintain air beam pressure, while filtering exhausted air. An internal air information monitoring system efficiently controls room air pressure and purifies the air. While a conventional negative pressure bed is reported to cost approximately 3.5 billion KRW (50 billion won for a ward), this module is estimated to cost 0.75 billion won each (10 billion won for a ward), cutting the costs by approximately 80%. The MCM is designed to be easily transported and relocated due to its volume, weight, and maintainability. This module requires only one-fourth of the volume of existing wards and takes up approximately 40% of their weight. The unit can be transported in a 40-foot container truck. “We believe this will significantly contribute to relieving the drastic need for negative pressure beds and provide a place for monitoring patients with moderate symptoms. We look forward to the MCM upgrading epidemic management resources around the world.” Professor Nam’s team is also developing antiviral solutions and devices such as protective gear, sterilizers, and test kits under the KAIST New Deal R&D Initiative that was launched to promptly and proactively respond to the epidemic. More than 45 faculty members and researchers at KAIST are collaborating with industry and clinical hospitals to develop the antiviral technology that will improve preventive measures, diagnoses, and treatment.
2021.01.07
View 11999
Team USRG’s Winning Streak Continues at the AI Grand Challenge
Team USRG (Unmanned Systems Research Group) led by Professor Hyunchul Shim from the School of Electrical Engineering has won the AI Grand Challenge 2020 held on Nov. 23 at Kintex in Ilsan, Kyonggi-do for the second consecutive year. The team received 7.7 million KRW in research funding from the Ministry of Science and ICT, the organizer of the challenge. The team took a little over two minutes to complete the rescue operation mission of the challenge. The mission included swerving around seven obstacles, airdropping an aid package, and safely landing after identifying the landing spot. Their drone is the only one that successfully passed through a 10-meter tunnel out of five pre-qualified teams: three from universities and two from companies. The AI Grand Challenge, which began in 2017, was designed to promote AI technology and its applications for addressing high-risk technical challenges, especially for conducting complex disaster relief operations. For autonomous flying drones, swerving to avoid objects has always been an essential skill and a big challenge. For their flawless performance in the rescue operation, the team loaded an AI algorithm and upgraded their drone by improving the LiDAR-based localization system and a stronger propulsion system to carry more sensors. The drone weighs 2.4 kg and carries a small yet powerful computer with a GPU. This AI-powered drone can complete rescue missions more efficiently in complicated and disastrous environments by precisely comprehending where the drone should go without needing GPS. The team also designed an all-in-one prop guard and installed a gripper onto the bottom of the drone to hold the aid package securely. “We tried hard to improve our localization system better to resolve issues we had in the previous event,” said Professor Shim. Two PhD candidates, Han-Sob Lee and Bo-Sung Kim played a critical role in developing this drone. After their two-year winning streak, their prize money now totals 2.4 billion KRW, equivalent to the winning prize of the DARPA Challenge. As the winning team, they will collaborate with other champions at the AI track challenge to develop rescue mission technology for a more complex environment. “The importance of AI technology is continuing to grow and the government is providing large amounts of funding for research in this field. We would like to develop very competitive technology that will work in the real world,” Professor Shim added. His group is investigating a wide array of AI technologies applicable to unmanned vehicles including indoor flying drones, self-driving cars, delivery robots, and a tram that circles the campus.
2020.12.01
View 8871
Virtual Commencement Ceremony Honors the Class of 2020
The KAIST community gathered online to celebrate the 2020 graduating class. The blended ceremony conferred their hard-earned degrees on August 28. The belated celebration, which was postponed from February 21 due to the COVID-19 outbreak, honored the 2846 graduates with live streaming on YouTube beginning at 2:00 pm. The graduates include 721 PhDs and 1399 master’s degree holders. The government raised its social distancing guidelines to level two out of three on August 23 as the second wave of the virus hit the nation. Level two guidelines prohibit the gathering of more than 50 persons indoors or 100 persons outdoors. For the virtual ceremony, the Office of Student Affairs and Policy announced a list of 67 graduates who signed up to participate in the graduation ceremony. Graduates were divided into three groups to attend at three different places and watch the ceremony via Zoom. No family and friends of the graduates were allowed to participate at the campus. This year’s valedictorian, Kon-Yong Lee from the Department of Chemical and Biomolecular Engineering, received the Award of Minister of Science and Technology. Salutorian Hee-Kwang Roh from the Department of Chemistry received the Award of the KAIST Board of Trustees, while the recipient of the KAIST Presidential Award was Hong Jae-Min from the School of Computing. President Sung-Chul Shin, Chairman of the Board of Trustees Woo-Sik Kim, former Minister of Science and Technology and former Provost at KAIST Dr. KunMo Chung, and a very limited number of faculty and staff members officiated the commencement ceremony from the KAIST auditorium. President Shin in his commencement speech applauded the graduates’ hard work and dedication and delivered a very special congratulatory message to them. He encouraged the new graduates to be courageous enough to deal with these new challenges as well as future uncertainties, during the greatest transformation brought about by COVID-19. “Instead of following behind others as a fast follower, we should take the initiative and walk down new paths as a first mover.” He also stressed, “We can transform this crisis into an opportunity by practicing the C3 values KAIST pursues: Challenging, Creating, and Caring.” As new alumni of Korea’s top science and technology university, he said, “Our graduates should focus on creating the world’s best, first, or only one in their research or their work.” However, he also pointed out the importance of a caring mind for others when working together. At the ceremony, KAIST conferred an honorary doctorate degree to Dr. Younghoon David Kim, CEO and Chairman of Daesung Group, in recognition of his lifetime dedication to making innovations in the energy industry. Daesung Group is a leading energy company in Korea which manufactures and supplies natural gas for industries and home users. Dr. Kim is committed to making efficient energy sources by advancing cutting-energy sciences and disruptive technologies. He has served as chairman of the World Energy Council since 2016. In his acceptance speech, Kim stressed the Grand Energy Transition as a new driving force in the future energy industry for maximizing energy efficiency. “Since energy is the most basic foundation for all industries, improvements in energy efficiency translate into benefits for all related industries in terms of its efficiency and productivity.” “The Grand Energy Transition is progressing widely and rapidly across the entire value chain of energy production, distribution, and consumption with decarbonization, decentralization, and digitalization serving as its driving force.” He went on, “We should regard energy efficiency not as the fifth fuel but the first primary fuel.” (END)
2020.08.28
View 11584
Professor Jaehyouk Choi, IT Young Engineer of the Year
Professor Jaehyouk Choi from the KAIST School of Electrical Engineering won the ‘IT Young Engineer Award’ for 2020. The award was co-presented by the Institute of Electrical and Electronics Engineers (IEEE) and the Institute of Electronics Engineers of Korea (IEIE), and sponsored by the Haedong Science and Culture Foundation. The ‘IT Young Engineer Award’ selects only one mid-career scientist or engineer 40 years old or younger every year, who has made a great contribution to academic or technological advancements in the field of IT. Professor Choi’s research topics include high-performance semiconductor circuit design for ultrahigh-speed communication systems including 5G communication. In particular, he is widely known for his field of the ‘ultra-low-noise, high-frequency signal generation circuit,’ key technology for next-generation wired and wireless communications, as well as for memory systems. He has published 64 papers in SCI journals and at international conferences, and applied for and registered 25 domestic and international patents. Professor Choi is also an active member of the Technical Program Committee of international symposiums in the field of semiconductor circuits including the International Solid-State Circuits Conference (ISSCC) and the European Solid-State Circuit Conference (ESSCIRC). Beginning this year, he also serves as a distinguished lecturer at the IEEE Solid-State Circuit Society (SSCS). (END)
2020.08.20
View 11350
Stress-Relief Substrate Helps OLED Stretch Two-Dimensionally
Highly functional and free-form displays are critical components to complete the technological prowess of wearable electronics, robotics, and human-machine interfaces. A KAIST team created stretchable OLEDs (Organic Light-Emitting Diodes) that are compliant and maintain their performance under high-strain deformation. Their stress-relief substrates have a unique structure and utilize pillar arrays to reduce the stress on the active areas of devices when strain is applied. Traditional intrinsically stretchable OLEDs have commercial limitations due to their low efficiency in the electrical conductivity of the electrodes. In addition, previous geometrically stretchable OLEDs laminated to the elastic substrates with thin film devices lead to different pixel emissions of the devices from different peak sizes of the buckles. To solve these problems, a research team led by Professor Kyung Cheol Choi designed a stretchable substrate system with surface relief island structures that relieve the stress at the locations of bridges in the devices. Their stretchable OLED devices contained an elastic substrate structure comprising bonded elastic pillars and bridges. A patterned upper substrate with bridges makes the rigid substrate stretchable, while the pillars decentralize the stress on the device. Although various applications using micropillar arrays have been reported, it has not yet been reported how elastic pillar arrays can affect substrates by relieving the stress applied to those substrates upon stretching. Compared to results using similar layouts with conventional free-standing, flat substrates or island structures, their results with elastic pillar arrays show relatively low stress levels at both the bridges and plates when stretching the devices. They achieved stretchable RGB (red, green, blue) OLEDs and had no difficulties with material selection as practical processes were conducted with stress-relief substrates. Their stretchable OLEDs were mechanically stable and have two-dimensional stretchability, which is superior to only one-direction stretchable electronics, opening the way for practical applications like wearable electronics and health monitoring systems. Professor Choi said, “Our substrate design will impart flexibility into electronics technology development including semiconductor and circuit technologies. We look forward this new stretchable OLED lowering the barrier for entering the stretchable display market.” This research was published in Nano Letters titled Two-Dimensionally Stretchable Organic Light-Emitting Diode with Elastic Pillar Arrays for Stress Relief. (https://dx.doi.org/10.1021/acs.nanolett.9b03657). This work was supported by the Engineering Research Center of Excellence Program supported by the National Research Foundation of Korea. -Profile Professor Kyung Cheol Choi kyungcc@kaist.ac.kr http://adnc.kaist.ac.kr/ School of Electrical Engineering KAIST
2020.02.27
View 9470
Professor Junil Choi Receives Stephen O. Rice Prize
< Professor Junil Choi (second from the left) > Professor Junil Choi from the School of Electrical Engineering received the Stephen O. Rice Prize at the Global Communications Conference (GLOBECOM) hosted by the Institute of Electrical and Electronics Engineers (IEEE) in Hawaii on December 10, 2019. The Stephen O. Rice Prize is awarded to only one paper of exceptional merit every year. The IEEE Communications Society evaluates all papers published in the IEEE Transactions on Communications journal within the last three years, and marks each paper by aggregating its scores on originality, the number of citations, impact, and peer evaluation. Professor Choi won the prize for his research on one-bit analog-to-digital converters (ADCs) for multiuser massive multiple-input and multiple-output (MIMO) antenna systems published in 2016. In his paper, Professor Choi proposed a technology that can drastically reduce the power consumption of the multiuser massive MIMO antenna systems, which are the core technology for 5G and future wireless communication. Professor Choi’s paper has been cited more than 230 times in various academic journals and conference papers since its publication, and multiple follow-up studies are actively ongoing. In 2015, Professor Choi received the IEEE Signal Processing Society Best Paper Award, an award equals to the Stephen O. Rice Prize. He was also selected as the winner of the 15th Haedong Young Engineering Researcher Award presented by the Korean Institute of Communications and Information Sciences (KICS) on December 6, 2019 for his outstanding academic achievements, including 34 international journal publications and 26 US patent registrations. (END)
2019.12.23
View 11385
Flexible User Interface Distribution for Ubiquitous Multi-Device Interaction
< Research Group of Professor Insik Shin (center) > KAIST researchers have developed mobile software platform technology that allows a mobile application (app) to be executed simultaneously and more dynamically on multiple smart devices. Its high flexibility and broad applicability can help accelerate a shift from the current single-device paradigm to a multiple one, which enables users to utilize mobile apps in ways previously unthinkable. Recent trends in mobile and IoT technologies in this era of 5G high-speed wireless communication have been hallmarked by the emergence of new display hardware and smart devices such as dual screens, foldable screens, smart watches, smart TVs, and smart cars. However, the current mobile app ecosystem is still confined to the conventional single-device paradigm in which users can employ only one screen on one device at a time. Due to this limitation, the real potential of multi-device environments has not been fully explored. A KAIST research team led by Professor Insik Shin from the School of Computing, in collaboration with Professor Steve Ko’s group from the State University of New York at Buffalo, has developed mobile software platform technology named FLUID that can flexibly distribute the user interfaces (UIs) of an app to a number of other devices in real time without needing any modifications. The proposed technology provides single-device virtualization, and ensures that the interactions between the distributed UI elements across multiple devices remain intact. This flexible multimodal interaction can be realized in diverse ubiquitous user experiences (UX), such as using live video steaming and chatting apps including YouTube, LiveMe, and AfreecaTV. FLUID can ensure that the video is not obscured by the chat window by distributing and displaying them separately on different devices respectively, which lets users enjoy the chat function while watching the video at the same time. In addition, the UI for the destination input on a navigation app can be migrated into the passenger’s device with the help of FLUID, so that the destination can be easily and safely entered by the passenger while the driver is at the wheel. FLUID can also support 5G multi-view apps – the latest service that allows sports or games to be viewed from various angles on a single device. With FLUID, the user can watch the event simultaneously from different viewpoints on multiple devices without switching between viewpoints on a single screen. PhD candidate Sangeun Oh, who is the first author, and his team implemented the prototype of FLUID on the leading open-source mobile operating system, Android, and confirmed that it can successfully deliver the new UX to 20 existing legacy apps. “This new technology can be applied to next-generation products from South Korean companies such as LG’s dual screen phone and Samsung’s foldable phone and is expected to embolden their competitiveness by giving them a head-start in the global market.” said Professor Shin. This study will be presented at the 25th Annual International Conference on Mobile Computing and Networking (ACM MobiCom 2019) October 21 through 25 in Los Cabos, Mexico. The research was supported by the National Science Foundation (NSF) (CNS-1350883 (CAREER) and CNS-1618531). Figure 1. Live video streaming and chatting app scenario Figure 2. Navigation app scenario Figure 3. 5G multi-view app scenario Publication: Sangeun Oh, Ahyeon Kim, Sunjae Lee, Kilho Lee, Dae R. Jeong, Steven Y. Ko, and Insik Shin. 2019. FLUID: Flexible User Interface Distribution for Ubiquitous Multi-device Interaction. To be published in Proceedings of the 25th Annual International Conference on Mobile Computing and Networking (ACM MobiCom 2019). ACM, New York, NY, USA. Article Number and DOI Name TBD. Video Material: https://youtu.be/lGO4GwH4enA Profile: Prof. Insik Shin, MS, PhD ishin@kaist.ac.kr https://cps.kaist.ac.kr/~ishin Professor Cyber-Physical Systems (CPS) Lab School of Computing Korea Advanced Institute of Science and Technology (KAIST) http://kaist.ac.kr Daejeon 34141, Korea Profile: Sangeun Oh, PhD Candidate ohsang1213@kaist.ac.kr https://cps.kaist.ac.kr/ PhD Candidate Cyber-Physical Systems (CPS) Lab School of Computing Korea Advanced Institute of Science and Technology (KAIST) http://kaist.ac.kr Daejeon 34141, Korea Profile: Prof. Steve Ko, PhD stevko@buffalo.edu https://nsr.cse.buffalo.edu/?page_id=272 Associate Professor Networked Systems Research Group Department of Computer Science and Engineering State University of New York at Buffalo http://www.buffalo.edu/ Buffalo 14260, USA (END)
2019.07.20
View 39876
Distinguished Professor Sang Yup Lee Honored with the 23rd NAEK Award
(Distinguished Professor Sang Yup Lee from the Department of Chemical and Biomolecular Engineering) Distinguished Professor Sang Yup Lee from the Department of Chemical and Biomolecular Engineering was honored to be the laureate of the 23rd NAEK Award. The NAEK (National Academy of Engineering of Korea) Award was instituted in 1997 to honor and recognize engineers who have made significant contributions to the development of the engineering and technology field at universities, industries, and institutions. Every year, it is conferred to only one person who has achieved original and world-leading research that has led to national development. Distinguished Professor Lee is a pioneering scholar of the field of systems metabolic engineering and he was recognized for his significant achievements in the biochemical industry by developing novel microbial bioprocesses. In particular, he is globally renowned for biological plastic synthesis, making or decomposing polymers with microorganisms instead of using fossil resources. He has produced numerous high-quality research breakthroughs in metabolic and systems engineering. In 2016, he produced an easily degradable plastic with Escherichia coli (E. coli). In 2018, he successfully produced aromatic polyesters, the main material for PET (poly ethylene terephthalate) from E. coli strains. He also identified microorganism structures for PET degradation and improved its degradability with a novel variant. His research was ranked number one in the research and development division of Top Ten Science and Technology News 2018 announced by Korean Federation of Science & Technology Societies. He is one of highly cited researchers (HCR) ranked in the top 1% by citations for their field by the Clarivate Analytics.
2019.03.21
View 8591
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