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Professor Chan Beum Park, requested for joint international research by a German biotechnology enterprise.
- Bitop AG (Germany) requested a joint development of medicines for Alzheimer’s disease
- The meaning of the financial support by European enterprise to the research result of domestic university.
Professor Chan Beum Park (Department of Materials Science and Engineering in KAIST/ President Nam Pyo Suh) has been entrusted with a joint international research for the development of medicines for Alzheimer’s disease from Bitop AG, German biotechnology enterprise.
KAIST recently agreed with Bitop AG to cooperate for a research program pursuing the development of inhibitors that inhibit the formation of plaque relevant to amyloid diseases like Alzheimer’s disease. Based on this agreement, KAIST will be provided with a financial support of sixty thousands Euro (about 74 million won) from Bitop AG.
Professor Park will perform the screening of inhibitors, which are the core of the research, and KAIST will share patent rights from the research with Bitop AG.
It is known that various degenerative nerve diseases like Alzheimer’s disease, Parkinson’s disease, mad cow disease, and so on arise mainly from the accumulation of pathological protein plaque termed amyloid, and environmental stress accelerates the diseases.
So far, no effective remedy has been developed for amyloid diseases.
Recently, the use of chemicals inhibiting the formation of amyloid has been raised as a potential remedy.
Natural small stress molecules extracted from microbes growing in extreme environments like volcanic region on the bottom of the deep sea, etc. are gaining attention as an amyloid inhibitor.
Professor Park found out for the first time in the world that Anti-stress materials are effective in inhibiting the formation of amyloid plaque and published that fact in several renowned European scientific journals.
After that, Professor Park was requested by Bitop AG for a joint research and has studied for the development of medicines for Alzheimer’s disease using various kinds of Anti-stress materials.
Professor Park said, “I’d like to grant a highly valuable meaning to this entrustment since it implies that European enterprises perceive the value of the research result by domestic universities and hope to promote research and development by providing practical financial support, etc. I wish this time’s entrustment will be a momentum to advance Korea’s research level one step higher through active joint researches with enterprises or institutes in U.S. and Europe as well as Bitop AG.”
Bitop AG is a German enterprise that produces various Anti-stress materials coming from extreme-loving microbes.
Currently, Anti-stress materials are being sold mainly as protein and cell protectants, cosmetic additives, health supplement, etc.
Anti-stress materials extracted from microbes well growing in extreme environment of one hundred centigrade or more are expected to perform a role of inhibitors that inhibit the formation of amyloid plaque, the main factor of stress-related degenerative nerve diseases like Alzheimer’s disease, etc. Such Anti-stress materials are gaining attention as a future medicine for Alzheimer’s disease, etc.
2006.09.05 View 15903 -
National NanoFab Center Established
NNFC Emerges with Cutting-edge Nanotech
On March 16, a dedication ceremony was held at KAIST to mark the completion of the National NanoFab Center(NNFC). The opening was graced with the presence of several prominent figures, namely, President Robert B. Laughlin, Daejeon City Mayor Hong-chul Yum, and Myung Oh, Deputy Prime Minister and Minister of Science and Technology.Celebrations of the opening were attended by roughly 300 related personnel. After a welcoming speech given by Hee-Chul Lee, President of NNFC, the event proceeded with a ribbon cutting ceremony, followed by a grand tour of the cleanroom.
The newly completed NNFC on campus boasts a total area of 17,035 square meters which consists of a four-storey research building, a cleanroom and a central utility building.
Still at the first stage of its equipment supplementation, the center has currently achieved an immense 140 in gear variety, worth approximately 80 billion won. At its final stage, a total of 206 equipment arrangements are to be available for various research purposes.
Implementing the use of state-of-the-art facilities, NNFC’s devices include an electron beam capable of critical measurements as small as ten nanometers and an ion beam structure for the analysis of nano-scale materials. These equipments are to be used in numerous areas - fundamental physics, biotechnology and nanoscience
Until the year 2011, a sum of 290 billion won is to be invested in the NNFC by the government and other private organizations. The center, along with Daedeok Techno Valley, aspires to play an integral role in maturing towards a new age of nanotechnology.
President Lee of the NNFC stated that the center is essential for Korea’s nanotechnology skills to achieve higher standards and compete with countries such as the U.S. and Japan. President Lee is also a professor of KAIST at the Division of Electrical Engineering.
By Kyoung-lee Park / Staff ReporterApril, 2005 / The KAIST Herald
2005.04.12 View 22514
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KAIST Develops Thinking, Feeling Human-Like Robot
By Kim Tae-gyu / Staff ReporterTHE KOREA TIMES 2005.1.31(page 1)
South Korean scientists created the world"s first artificial species, a software robot with ``genes"" and ``chromosomes.""
Kim Jong-hwan, professor at Korea Advanced Institute of Science and Technology, said Sunday his team had developed a robot with 14 chromosomes, which gives the machine a ``personality.""
``This robot is a software-based one, sometimes called a sobot. It has a unique synthetic character determined by its specific combination of 14 chromosomes,"" the 47-year-old Kim said.
When Kim"s team gave a stimulus to the chromosome-equipped sobots, they showed totally different responses even under the same environment due to their distinctive personalities.
Several cognitive sensors enable the prototype models to identify 47 differing outside stimuli. The virtual robots also have 77 behavior patterns.
``Because a sobot is basically a software system, it can easily travel to other robots and multiply. In the middle of such processes, it can evolve through crossover and mutation,"" Kim said.
With the development of associated technologies, Kim expected the number of chromosomes would be augmented as sobots evolve to a more sophisticated species in the future.
The capacity to load large volumes of data is related to the evolution of sobots. Currently, 14 chromosomes consist of roughly 2,000 bytes of data.
The effort to incorporate the sobot into a platform, robot hardware, is now underway and Kim"s team looks to unveil the new-concept species as soon as next month.
``Diverse behavior patterns driven by sobots" specific personalities will be precisely translated into action just like the soul rules the body,"" Kim said.
Kim did not think the robotic evolution would lead to the human race being threatened; the concept of the recent blockbuster ``I, Robot.""
``If we design the chromosomes safely, the self-reproducing robot will not post a threat back to us,"" Kim said.
Kim first revealed the robotic breakthrough at a keynote speech of the International Conference on Autonomous Robots and Agents, held in New Zealand last December.
Kim is also known as pioneer in the field of robot football and has headed the Federation of International Robot-soccer Association (FIRA) since its foundation in 1999.
voc200@koreatimes.co.kr
2005.02.02 View 17147
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Nerve-protecting gene discovered
Korean scientists for the first time have identified a gene that blocks nerve damage from fevers and the use of narcotics, a state-run research institute said yesterday.
The finding may open the way for new medicine that can prevent the loss of brain function which is frequently caused by excessive stimulation of nerves and abnormally high body temperature.
"The research is in an early stage. But this approach has the potential to develop genetics-based preventatives against brain-attacking diseases," said Kim Jae-seob, a bioscience professor of the Korea Advanced Institute of Science and Technology, who led the study.
The researchers named the gene Pyrexia, which means fever. Kim"s team extracted it from genetically engineered fruit flies using a genome-screening system. In laboratory tests, they found that the gene is activated to 39 degrees Celsius or higher.
The researchers enhanced Pyrexia"s functionality in some fruit flies while removing the gene from others to observe their different reactions when exposed to high temperature.
"The fruit flies without the gene showed severe nerve disorder and suffered paralysis of brain function, while Pyrexia-enhanced flies maintained their normal brain conditions," the professor said.
The researchers got the same result from experiments with human cells, he said.
There are a lot of channel proteins, which enable ions to enter and exit the cell, that react to the level of temperature, but Pyrexia is the first of its kind that actually protects the neurons from external stimulus, he said.
The finding will appear on the March edition of the London-based science magazine Nature Genetics.
THE KOREA HERALD 2005.1.31 (thkim@heraldm.com) By Kim Tong-hyung
2005.02.02 View 15953
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Gene Protecting Brain Nerves Discovered
THE KOREA TIMES 2005.1.31By Kim Tae-gyu / Staff Reporter
South Korean scientists have for the first time discovered genes tasked with protecting brain nerves.
Korea Advanced Institute of Science and Technology professor Kim Jae-seob said Sunday the new genes, named pyrexia, shield brain nerves from outside stimuli, including high temperatures.
``The channel gene of pyrexia will open the door to developing new-concept medicines for brain damage in patients of high fever or drug addicts,’’ he said.
The channel gene refers to transport proteins, which provide a static passageway for a variety of essential substances to enter into cells.
``Up until now, a lot of channel genes activated by temperatures have been identified. But among them, pyrexia is first that guards brain nerves from external stresses,’’ Kim said.
Kim’s team learned pyrexia plays a pivotal role in the body through experiments with genetically engineered flies that did not have any pyrexia.
Up to 60 percent of the pyrexia-depleted mutants were paralyzed within three minutes of exposure to a temperature of 40 degrees Celsius.
In comparison, just 9 percent of normal flies were paralyzed with the same stimulus, indicating pyrexia is responsible for protecting animals from high-temperature stress.
``Our next goal is to develop pyrexia-embedded drugs, which can be expected to commercially debut in about five years,’’ Kim said.
Kim has already applied for international patents for his medical breakthrough, which will be printed in the March edition of Nature Genetics, a science journal.
voc200@koreatimes.co.kr
2005.02.02 View 15666
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KAIST-Tsinghua High-Tech EXPO 2004
THE KAIST Herald 2004.5.12
By Jong-kyoung KimThe KAIST Herald Staff Reporter
KAIST and Tsinghua University are holding KAIST-Tsinghua Korea-China High Tech EXPO 2004 from July 12 to 14, at the Beijing International Convention Center. The Expo seeks to contribute to economic development through promoting exchanges between exceptional Korean and Chinese start-up companies, and to promote cooperation between high-tech industries and academic institutions through academic and technological exchanges between each nation"s best technology institutions.
The Expo is a big international affair held by a university from Korea and one from China. The Expo is also a means to implement the agreement between KAIST and Tsinghua in 2002 to promote exchanges between the two universities and to conduct international co-research. It is sponsored by various technology institutions of both nations.
The Expo is different from other expos in that it is a specialized expo where Tsinghua-related companies, experts, and buyers participate to discuss the transfer of technologies and to deal in trades. Also, to insure that the Expo is beneficial to participating Korean companies, the Expo plans to offer business talks with at least ten Chinese companies per company. From Korea, thirteen companies from enterprise-incubation center and graduate start-ups with high-tech start-ups in areas of IT, BT, NT and mechatronics that are possible in exporting related products or transferring related technologies are participating. From China, Tsinghua-related companies, China Telecom, China Unicom, and other companies under China Telecommunication Association with other famous Chinese companies are expected to participate.
In addition to exhibitions, co-work between KAIST and Tsinghua"s research centers and KAIST"s Technology Transfer & Exchange Center"s explanation on public technology transfer are taking place during the Expo.
And, after three days of the Expo, about ten companies will move to Chungking, a city in western China to hold a product and technology explanation session.
2004.05.21 View 20460
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18th Student Council Elected
The KAIST Herald December 3, 2003
The votes were cast and counted on November 27. Donggodongrak won the election of the 18th Undergraduage Student Council of Korea Advanced Institute of Science and Technology (KAIST). Of the 2,340 eligible voters for the 18th student council election, 1,304 votes, or about 56 percent of the total, were amassed after a full day of election on November 27.
The two candidate teams, waiting to hear the result with much anxiety, were juniors Hye-min Kim and Jung-mo Kim running for the president and vice president positions, respectively, of the team "Donggodongrak" and juniors Dong-geun Kim and Yong-jae Yoon running for the same positions, respectively under the name "Woorung Chonggak."
Donggodongrak secured over 58 percent of the votes, with 760 supporting ballots, while Woorung Chongak polled 503 votes, or about 39 percent of the votes. Forty-one votes, or three percent of the votes cast were spoiled votes. With more than half the voters having participated, the election was valid, and Donggodongrak was declared the new student council of KAIST.
The election platform of the Donggodongrak team largely consist of four themes, composed of several smaller goals. First, they assert the "togetherness" of the student government and plan to achieve it by publishing monthly newsletters, hosting an open outdoor student council every other week, and creating various committees.
Secondly, they assert under the theme of an "improving" student government that they will promote festivals and events among the sixteen departments, form an official "class" of the freshmen, and broaden the association of the student representatives.
Third, Donggodongrak declares it wants to create an "open and just environment" by holding periodic meetings with the school for direct discussions of school policies; and by taking care of the welfare of the students in detail.
Finally, they advocate "a student government that communicates with society"; they will support opportunities to become more aware of various issues of society.
President Hye-min Kim, a graduate of Pusan Science High School, has participated in various intramural, socially active groups, and is majoring in applied mathematics. Vice-president Jung-mo Kim is a graduate of Mokpo High School and studies mechanical engineering.
2004.03.15 View 20866
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Professor Yang Receives Academic Award
By Ki-beom Lee / Reporter
The KAIST Herald December 3, 2003
The Professor Dong-yol Yang of the Department of Mechanical Engineering received the Sang-woo Academic Award last month. Unlike other awards of similar nature, this award is given to one of many leading scientists who has written six to seven papers in the previous year. This award is special in that Professor Yang retired as chairman of the Korean Society for Technology of Plasticity in December 2002. Professor Yang received a prize on the research of the anisotropic pressing out process. He has also written papers based on the twenty-five years of research at Korea Advanced Institute of Science and Technology and has researched high-speed modeling for the first time in Korea.
2004.03.15 View 18523