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KAIST Controls the Rotation Direction of Light Without Complex New Materials
A new pathway has opened for controlling the rotation direction of light simply by changing how molecules are arranged, without having to synthesize complex new materials. Circularly polarized light is a special form of light that travels while rotating like a pinwheel either to the left or to the right. Because different rotation directions can carry different information, it is drawing attention as a key light source for next-generation displays, optical communications, and security technologies. KAIST researchers have developed a platform technology that arranges symmetric molecules into “microscopic pinwheels,” enabling circularly polarized light with a desired rotation direction.
KAIST (President Choongsik Bae) announced on August 14 that a research team led by Professor Dong Ki Yoon from the Department of Chemistry, in collaboration with researchers from Chungnam National University, Ajou University, Yonsei University, and Japan’s RIKEN, has developed a technology that spatially confines symmetric non-chiral liquid crystal molecules and applies an electric field to form micrometer-scale chiral pinwheel structures, then permanently replicates them onto polymer nanofibers.
Chirality refers to the property of an object whose mirror image cannot be perfectly superimposed on the original, like a person’s left and right hands. Chirality is a key property not only of biological molecules such as proteins and DNA, but also of optical materials used in next-generation displays, optical sensors, and optical communications.
Until now, producing chiral optical materials has generally required the complex synthesis of molecules with asymmetric structures or the addition of large amounts of chiral substances. This has made fabrication complicated, limited the range of usable materials, and made it difficult to realize chiral structures with the same handedness over a large area.
To address this challenge, the research team proposed a new approach based on the idea that “structure creates function.”
The team applied to molecules the same principle by which the same sheet of paper can form either a clockwise or counterclockwise pinwheel depending on how it is folded. They focused on the fact that even symmetric molecules can form structures with different handedness depending on how they assemble.
The researchers first induced rod-shaped molecules to self-assemble into microscopic pinwheel-like structures. They then added an extremely small amount of chiral additive, less than 1% of the total material, to guide all of the pinwheels to face the same direction. The team then successfully replicated this structure onto polymer nanofibers.
When a conventional luminescent material was coated onto this structure, circularly polarized light rotating in opposite directions was emitted depending not on the luminescent material itself, but on the direction of the pinwheel structure. Circularly polarized light is a special form of light that rotates to the left or right as it travels, and because each rotation direction can carry different information, it can be used in next-generation displays, optical communications, and anti-counterfeiting technologies.
In other words, the study showed that the properties of light can be controlled simply by changing the structure on which a light-emitting material is placed, rather than by changing the light-emitting material itself. Put simply, just as the same LEGO blocks can form completely different shapes depending on how they are assembled, the same molecules can produce different optical properties depending only on how they are arranged.
Professor Dong Ki Yoon said, “The key point of this study is that we controlled the rotation direction of light not through the complex chemical structure of chiral molecules, but only through the way molecules are arranged,” adding, “This work presents a new optical material design principle that can be applied to next-generation displays, AR and VR optical devices, polarization sensors, and optical communications without the need to develop complex new materials.”
Jeong Yeon Han, the first author and a Ph.D. candidate, explained, “In conventional approaches, left-handed and right-handed structures tended to form together, canceling out chiral properties. In this study, however, we succeeded in aligning the structures in a single direction over a large area by designing an extremely small amount of additive to select only one rotation direction.”
This study was led by Ph.D. candidate Jeong Yeon Han as the first author, and the research results were published in the international journal Nature Communications on August 05.
Paper title: Microchiral pinwheel arrays based on achiral molecules,
DOI: 10.1038/s41467-026-76089-z
Authors: Jeong Yeon Han (first author), Won Kyung Park, Byeongil Noh, Fumito Araoka, Sungwook Jung, Byeong Hak Jhun, Youngmin You, Yoonsu Park, Kyung Jin Lee*, Jung-Moo Heo*, and Dong Ki Yoon* (*corresponding authors)
This research was supported by the Technology Innovation Program of the Ministry of Trade, Industry and Energy, the InnoCORE Program of the Ministry of Science and ICT, and the National Research Foundation of Korea.
2026.08.14 View 69 -
KAIST and Samsung Heavy Industries Launch Advanced Maritime Research Center, Marking 32 Years of Industry–Academia Collaboration
KAIST (President Choongsik Bae) announced that it held an opening ceremony for the SHI–KAIST Advanced Maritime Research Center (AMRC) with Samsung Heavy Industries (Vice Chairman and CEO Sung-an Choi) on August 13 at the John Hannah Hall in KAIST Academic Cultural Complex on its main campus in Daejeon.
The new center marks a major milestone in the 32-year industry–academia partnership between the two institutions, which dates back to 1995. Building on more than three decades of joint research and mutual trust, KAIST and Samsung Heavy Industries are expanding their partnership through a joint research hub dedicated to developing key technologies for the future of the shipbuilding and offshore industries.
Through the center, the two institutions will jointly develop technologies that address industry needs in areas including AI, robotics, and green technologies. They will also work to bring research outcomes into industrial applications and develop highly skilled professionals.
“Physical AI that drives innovation in real-world industrial settings will be a determining factor in manufacturing competitiveness,” said KAIST President Choongsik Bae. “The shipbuilding and offshore industry is a prime field for creating new value through the convergence of mechanical engineering, AI, and robotics. I hope the center will grow into a research hub that addresses challenges facing industry and sets new benchmarks for future technologies.”
“It is especially meaningful to see our 32 years of collaboration with KAIST culminate in the establishment of the Advanced Maritime Research Center,” said Sung-an Choi, Vice Chairman and CEO of Samsung Heavy Industries. “We will further accelerate our efforts to secure technological competitiveness and foster talent for the future shipbuilding and offshore industry in areas including autonomous navigation, eco-friendly vessels, and smart manufacturing.”
To secure key technologies for the future shipbuilding and offshore industry, the center will conduct joint research in four areas. AI technologies for autonomous operation and intelligent navigation; propulsion systems using zero- and low-carbon fuels; manufacturing innovation for smart shipyards and digital twins; and robotics specialized for shipbuilding and offshore applications.
In autonomous navigation, researchers will develop AI algorithms for advanced autonomous navigation systems, including technologies for situational awareness, optimal route planning, and collision avoidance. The center will also conduct research on zero- and low-carbon fuels in response to international efforts toward carbon neutrality and the green transition of the shipping and shipbuilding industries. This work will focus on key vessel components and fuel-supply technologies for clean fuels such as ammonia and hydrogen.
In the area of smart shipyards, the center will use AI and digital twin technologies to optimize complex shipbuilding processes, including block erection and production management. This research aims to improve productivity and quality while reducing costs and energy consumption. In specialized maritime robotics, researchers will develop technologies to automate demanding on-site tasks such as welding, painting, and inspection. These technologies will help address the decline in the working-age population while improving worker safety and production efficiency.
Beyond technology development, the center will serve as a hub for training specialists who will lead the future maritime industry. The two institutions will use industry–academia cooperation funding and other resources to support student research and scholarship programs. They will also expand personnel exchange programs connecting industrial sites and research laboratories, thereby continuously fostering research talent with the practical, industry-relevant capabilities needed in the field.
The center was established on the foundation of more than three decades of cooperation between the two institutions. Their partnership began in 1995, when Samsung Heavy Industries’ Ship & Offshore Research Institute and KAIST’s Department of Mechanical Engineering established the SHI–KAIST Industry–Academia Cooperation Council. Since then, they have conducted joint research spanning the shipbuilding and offshore engineering fields—including structures, fluid dynamics, cryogenics, green technologies, smart ships, and autonomous navigation—and accumulated a broad base of foundational technologies.
The institutions have continued to strengthen the connection between research and industry through initiatives such as the Advisory Board program, industry-tailored courses, and joint SEED research projects. The number of collaborative projects and technical consulting cases conducted through the Advisory Board program has exceeded 1,000. The two institutions have also maintained active personnel exchanges through short-term researcher training and cooperative education programs.
Approximately 50 people attended the opening ceremony to celebrate the launch of the center, including KAIST President Choongsik Bae, faculty members and professors emeriti from the Department of Mechanical Engineering, Samsung Heavy Industries Vice Chairman and CEO Sung-an Choi, and other executives and officials.
2026.08.13 View 98 -
KAIST brings ‘giant batteries’ closer to commercialization in the AI data center era
The explosive growth of AI data centers has brought the commercialization of "giant batteries" one step closer. A KAIST research team has developed a process that cuts the production time for a core material used in large-capacity batteries by 67%, resolving the largest production bottleneck standing in the way of commercialization.
KAIST (President Choongsik Bae) announced on August 5 that a research team led by Professor Hee-Tak Kim from the Department of Chemical and Biomolecular Engineering has developed a process for producing the core electrolyte of vanadium redox flow batteries (VRFBs)—a leading candidate for large-capacity energy storage systems (ESS)—faster and more stably.
As AI data centers operate around the clock in growing numbers, large-capacity ESS that can store electricity generated from solar and wind power and supply it reliably when needed have become increasingly important.
Because VRFBs use nonflammable, water-based electrolytes, they have a lower fire risk than many conventional battery systems. And their energy-storage capacity can be scaled by increasing the amount of electrolyte stored in external tanks. This has drawn attention to VRFBs as ultra-large batteries suited to AI data centers and renewable energy storage. However, producing the vanadium electrolyte with an average oxidation state of 3.5+—the standard starting composition for VRFB operation— has been slow and costly, making it a critical obstacle to commercialization.
The conventional process first produces the electrolyte through chemical reduction—a reaction in which a chemical reducing agent causes vanadium ions to gain electrons—and then refines it through electrochemical reduction, which applies electric current to adjust the vanadium ions' electron state to the desired level. This final electrochemical step, however, relies on a costly VRFB stack and significant electrical energy, increasing both operational complexity and capital costs.Beyond the limitations of the electrochemical reduction process, the research team found, for the first time, that the alternative chemical reduction process also suffers from a distinct kinetic bottleneck. The reaction rate slows sharply at a specific point, much like highway traffic suddenly backing up at a bottleneck. This bottleneck occurs when the average vanadium oxidation state reaches approximately +4.1, an intermediate stage in the production of V3.5+ electrolyte.
In previous research, the team had replaced the conventional electrochemical adjustment step with a Pt/C-catalyzed reduction process, preventing the waste of leftover electrolyte. In the present study, it further extended the catalytic process into the bottleneck region of oxalic-acid-based chemical reduction. By switching from chemical to catalytic reduction at an average oxidation state of approximately +4.1, the team was able to bypass the slowest stage of the production process.
As a result, production time for V3.5+ electrolyte was cut by 67% compared to the conventional process. The switch also eliminated residual oxalic acid, an impurity that can degrade battery performance. The same catalyst was reused more than 2,500 times without a notable drop in performance, demonstrating the process's viability for industrial-scale production.
"This study combined reaction engineering principles with thermodynamic predictions to identify the rate-determining step in the chemical reduction and redesigned the electrolyte production process to overcome this major bottleneck to the commercialization of large-scale batteries," said Hee-Tak Kim, professor in the Department of Chemical and Biomolecular Engineering. He added, "By scientifically identifying the conditions under which the catalyst operates stably without degrading in the electrolyte environment, we resolved a production bottleneck relevant to industry, and we expect this to significantly accelerate the commercialization of large-capacity energy storage technology."
Kyunghwa Seok, a PhD candidate in the Department of Chemical and Biomolecular Engineering, led the research as first author. The findings were published online in Advanced Energy Materials—a leading international journal in the energy field—on May 7. In particular, in recognition of its academic significance, the study was selected as the cover article for Issue 34, which is scheduled to be published online in early September.
Paper title: Streamlined V3.5+ Electrolyte Production by Leveraging Chemical and Catalytic Reductions
DOI: https://doi.org/10.1002/aenm.71029
Authors: Kyunghwa Seok (KAIST, first author), Minseong Kang (KAIST, second author), and Hee-Tak Kim (KAIST, corresponding author).
This research was supported by Lotte Chemical.
2026.08.05 View 590 -
KAIST Develops Marine Carbon Removal Technology That Turns Carbon Dioxide in Seawater into “Stone” for Permanent Storage
A new pathway has opened to enhance the ocean’s natural ability to clean the planet. KAIST researchers have developed a technology that converts carbon dioxide dissolved in seawater into “stone,” or minerals, preventing it from returning to the atmosphere and enabling permanent storage. The achievement is expected to help the ocean absorb more carbon dioxide and accelerate the commercialization of next-generation marine carbon removal technologies.
KAIST (President Choongsik Bae) announced that a research team led by Professor Dong-Yeun Koh from the Department of Chemical and Biomolecular Engineering, in collaboration with Professor T. Alan Hatton’s group at the Massachusetts Institute of Technology (MIT), has developed an electrochemical dissolved ocean carbon removal (e-DOC) technology that converts carbon dioxide dissolved in seawater into calcium carbonate (CaCO₃), a stable mineral form, enabling virtually permanent carbon storage.
The ocean is the planet’s largest carbon reservoir, absorbing about 30% of the carbon dioxide emitted by human activity. Just as water naturally refills a large container when some is removed, removing carbon dioxide from seawater enables the ocean to absorb more carbon dioxide from the atmosphere.
The research team developed a technology that converts dissolved inorganic carbon (DIC), the carbon species dissolved in seawater, into a mineral form that does not return to the atmosphere. Once stored in this form, the carbon is effectively prevented from returning to the air, allowing the ocean to continue absorbing new carbon dioxide. Such technologies are gaining attention as key carbon dioxide removal (CDR) solutions for responding to climate change.
However, conventional technologies have faced a major challenge: mineral scaling. Much like limescale building up inside a kettle, minerals such as calcium carbonate adhere to electrode surfaces and clog the system. As operation continues, performance declines, requiring frequent cleaning or replacement of components and increasing both energy consumption and maintenance costs.
To overcome this issue, the research team developed a hollow fiber electrode assembly (HFEA), a device composed of bundled hollow, thread-like electrodes. In this structure, minerals form outside the electrode surface rather than directly on it, while hydrogen bubbles naturally generated during the reaction act like a brush, continuously cleaning the electrode surface and preventing mineral buildup.
In experiments using Jeju lava seawater, the team successfully operated the device continuously and stably for more than 120 hours. The system removed 80–90% of dissolved inorganic carbon from seawater and reduced electricity consumption by up to 54% compared with existing technologies. In addition, the process simultaneously produced high-purity hydrogen (H₂) and magnesium hydroxide (Mg(OH)₂), a material used in eco-friendly products and industrial applications, further improving its economic potential.
The newly developed device can be produced in a compact, modular form, making it suitable for installation on ships, offshore plants, and other marine industrial facilities. The research team expects the technology to be scaled up into large-scale marine carbon removal systems that can contribute to achieving carbon neutrality and responding to climate change.
Professor Dong-Yeun Koh said, “This technology converts carbon dioxide dissolved in seawater into a mineral form that does not return to the atmosphere, enabling permanent storage and helping the ocean continuously absorb new carbon dioxide,” adding, “We expect this work to accelerate the commercialization of marine carbon removal technologies and contribute to the realization of a carbon-neutral society.”
This study was co-led by KAIST Ph.D. candidate Inhwan Park of the Department of Chemical and Biomolecular Engineering and Dr. Young Hun Lee of MIT, who received his Ph.D. from KAIST in 2023 and is currently affiliated with the Department of Chemical Engineering at MIT, as co-first authors. The paper was published online on June 19, 2026, in the international journal Advanced Energy Materials.
Paper title: A Compact Hollow Fiber Electrode Assembly Architecture for Continuous Electrochemical Marine Carbon Dioxide Removal
DOI: https://doi.org/10.1002/aenm.71205
This research was supported by Hyundai Motor Company and Kia, as well as the Global C.L.E.A.N. Program of the National Research Foundation of Korea funded by the Ministry of Science and ICT.
2026.08.04 View 681 -
KAIST Develops AI That Finds Its Own Hidden Weaknesses, Paving the Way for Safer Generative AI Models
KAIST researchers have developed a safety verification technology that uncovers roughly seven times more hidden vulnerabilities in AI than existing methods. The technology is expected to serve as a foundation for developing safer, more trustworthy AI.
KAIST (President Choongsik Bae) announced on the 30th of July that a research team led by Professor Junmo Kim from the School of Electrical Engineering has developed a new framework called Stable-GFlowNet (S-GFN), which overcomes the limitations of red-teaming—a safety verification process that deliberately attacks large language models (LLMs) to expose hidden weaknesses.
Red-teaming for generative AI is the process of crafting attack prompts designed to probe an AI's vulnerabilities and induce the AI to produce harmful or dangerous responses before the program is deployed. Since discovering a wider variety of attack methods allows more vulnerabilities to be addressed in advance, both the success rate and diversity of attacks are critical.
Previous approaches primarily relied on reinforcement learning—an AI technique trained to maximize reward—to generate attack prompts. However, these methods frequently suffered from mode collapse—a phenomenon where the model repeatedly converges on a narrow set of high-reward attack prompts rather than generating diverse outputs, thereby limiting its ability to uncover various vulnerabilities.
Generative Flow Networks (GFlowNets)—an AI generation technique trained to produce diverse outputs in proportion to their reward—were proposed as a solution. Yet GFlowNet training is computationally complex and unstable, and noisy reward signals can assign high rewards even to meaningless sentences, often causing training to collapse.
To address these issues, the research team developed three core techniques that help the model learn effective attacks more reliably while filtering out flawed ones.
First, much like comparing several paths to choose the best one, the team introduced Contrastive Trajectory Balance (CTB), which reduces computational complexity and stabilizes training by directly comparing pairs of generated attack trajectories.
Second, akin to filtering out background noise to focus on a single voice, the team applied Noise Gradient Pruning (NGP) to eliminate minor reward fluctuations and ensure the model learns exclusively from meaningful signals.
Third, the team applied the Min-K Fluency Stabilizer (MKS), which guides the model to generate attack prompts resembling text that a real user would write—just as a human reader naturally prefers coherent sentences to gibberish.
As a result, Stable-GFlowNet discovered 134 unique attack types—about seven times more than the 17 unique attack types found by the existing GFlowNet-based technique—while maintaining a high attack success rate of 92%.
Defense models trained using attacks generated by Stable-GFlowNet also demonstrated strong generalization, effectively defending against a wide range of attacks in cross-attack tests, which evaluate performance using attack techniques different from those used during training.
The team further demonstrated that CTB and NGP achieve faster and more stable performance than existing methods—not only in AI safety verification, but also in other distribution-matching tasks such as molecular generation for drug discovery.
Professor Kim said, "This technology is significant in that it can reliably uncover a wide range of AI vulnerabilities even in realistic conditions with limited data and high noise." He added, "Because it allows a broader range of risk factors to be identified and defended against before generative AI is deployed in real-world services, we expect it to become a core foundational technology for developing safer, more trustworthy AI."
The study was led by first author Minchan Kwon, a Ph.D. candidate from the School of Electrical Engineering, and was selected as a Spotlight paper—placing it in the top 2.2% of submissions—at the International Conference on Machine Learning (ICML) 2026, one of the world's most prestigious AI conferences.
※ Paper title: Stable-GFlowNet: Toward Diverse and Robust LLM Red-Teaming via Contrastive Trajectory Balance
arXiv: https://arxiv.org/abs/2605.00553
This research was supported by the Institute of Information & Communications Technology Planning & Evaluation’s (IITP) SW Star Lab program, funded by the Ministry of Science and ICT.
2026.07.30 View 877 -
KAIST Professor Sooel Son Selected for Microsoft Funding for AI Safety and Security Research
KAIST (President Choongsik Bae) announced on the 28th of July that Professor Sooel Son has been selected as the only researcher in Korea to receive funding from Microsoft for research on artificial intelligence safety and security.
The funding was awarded through the External Red Team Alliance (EXTRA), a new program established by Microsoft’s AI Red Team, which examines the safety and security vulnerabilities of AI systems. EXTRA is a global initiative designed to strengthen AI safety and security research capabilities by supporting researchers at universities and technology experts around the world.
Microsoft noted that most AI safety testing is still conducted internally by individual companies or organizations. However, assessing the major risks posed by increasingly advanced AI systems requires expertise across a broad range of fields, including cybersecurity, multilingual environments, regional and cultural contexts, AI alignment, and potential misuse. EXTRA was launched in recognition of the difficulty a single internal organization faces when comprehensively evaluating these diverse risks.
Through the program, Microsoft will provide KAIST with an unrestricted gift of USD 25,000, approximately KRW 37 million, with no prescribed project period, to support research related to AI safety, security, alignment, and responsible AI development. The funding will be used to support Professor Son’s research team in its work on AI security and safety.
More than a dozen universities across six continents are participating in EXTRA, with KAIST being the only university selected from Korea. Through the program, Microsoft plans to expand the ecosystem for independent AI safety research and strengthen collaboration between academia and industry.
Professor Son’s research team has been conducting research on the security and privacy of AI systems that use machine-learning models and large language models. In particular, the team analyzes adversarial attacks against deep neural networks and language models—including model extraction, membership inference, personal information extraction, model inversion, machine unlearning, and prompt injection—and develops defense methodologies to assess and improve model safety.
Building on these technologies, the team is also focusing on establishing systematic defense methodologies that enable the safe and trustworthy deployment of agentic AI systems operating in real-world service environments, including web agents and agentic browsers.
“As AI systems rapidly spread throughout society, research that verifies the security and reliability of increasingly advanced AI is becoming more important,” said Professor Son. “Our participation in Microsoft AI Red Team’s EXTRA program will provide an opportunity to further advance our research on the safe development and use of AI systems.”
“AI safety research has never been more important, and universities have a critical role to play in advancing the field,” said Ram Shankar Siva Kumar, who leads the Microsoft AI Red Team. “Through EXTRA, we aim to support researchers working to deepen our understanding of how increasingly powerful AI systems can be evaluated, protected, and governed responsibly.”
“Competition in AI technology is expanding beyond performance to encompass safety and trustworthiness,” said KAIST President Choongsik Bae. “KAIST’s participation as the only Korean research institution in Microsoft’s global AI safety research network is a meaningful achievement that demonstrates Korea’s competitiveness in AI research. We will continue to lead the advancement of responsible AI technologies that everyone can trust and use by pursuing world-class research in AI safety and security.”
2026.07.28 View 1262 -
KAIST identifies a molecular “switch” that activates cell growth signaling, suggesting a potential basis for next-generation anticancer therapy
Cells carry their own growth switches. When enough nutrients—amino acids in particular—are available, cells flip this switch on and begin to grow. Researchers at KAIST and Yonsei University have now uncovered the molecular mechanism by which amino acid signals activate this cellular growth switch. The findings are expected to open a new avenue for anticancer therapies that target abnormal growth signaling in tumor cells.
KAIST (President Choongsik Bae) announced on July 26 that a research team led by Professors Hee-Sung Park and Jin Young Kang from the Department of Chemistry, working with Professor Sunghoon Kim's team from Yonsei University, has identified a molecular mechanism that links amino acid stimulation to mTORC1-dependent growth signaling.
Cells continually monitor whether enough amino acids—the basic building blocks of proteins—are available in their surroundings, and adjust their growth, protein synthesis, and energy use accordingly. Central to this process is mTORC1 (mammalian Target of Rapamycin Complex 1), a protein complex that functions as the cell's growth switch.
mTORC1 promotes cell growth, protein synthesis, and metabolism when nutrients and energy are abundant. But when mTORC1 becomes excessively active, cells can grow and proliferate beyond what is needed—a pattern of dysregulation observed in numerous cancers. For this reason, mTORC1 has long been considered a prime target for anticancer drug development. Exactly how cells detect external nutrient cues and translate them into mTORC1 activation, however, has remained incompletely understood.
The research team focused on the multi-tRNA synthetase complex (MSC), a large protein assembly composed of multiple aminoacyl-tRNA synthetases and scaffold proteins. While aminoacyl-tRNA synthetases are best known for their essential role in protein synthesis – attaching specific amino acids to their cognate tRNAs – the team showed that, in response to amino acid stimulation the MSC releases LARS1, thereby linking nutrient availability to growth signaling.
The key player within the MSC turned out to be a protein called LARS1 (leucyl-tRNA synthetase 1), an enzyme that attaches leucine to its corresponding tRNA and also functions as an intracellular leucine sensor. When cells receive a signal that nutrients are sufficient, LARS1 undergoes phosphorylation—a modification in which a small chemical tag is attached to a protein, altering its function or binding behavior.
The relationship can be pictured this way: the MSC is a control center where multiple proteins wait on standby, and LARS1 is the field agent dispatched to flip on the growth switch. When nutrients become abundant, LARS1 receives a phosphorylation "deployment signal," dissociates from IARS1, the protein that anchors LARS1 to the MSC, and is thereby released from the complex. The freed LARS1 then goes on to activate mTORC1.
In other words, when nutrients are scarce, LARS1 stays bound within the MSC and the growth signal remains off. Once nutrients become sufficient, LARS1 is released from the MSC and switches on mTORC1.
To investigate the structural basis of this process, the team used cryo-electron microscopy (cryo-EM), a technique that visualizes protein complexes in three dimensions in near-atomic resolution by rapidly freezing samples at extremely low temperatures. This allowed the researchers to determine how LARS1 and IARS1 bind to each other and to structurally explain how phosphorylation could disrupt their interaction.
The results showed that LARS1 and IARS1 are normally bound tightly, but amino acid stimulation induces the phosphorylation of LARS1, weakening its interaction with IARS1. This allows LARS1 to dissociate from the MSC and activate mTORC1.
The researchers also engineered phosphomimetic LARS1 variants—mutant proteins designed to imitate the phosphorylated state—and found that these variants substantially enhanced mTORC1 activity. This confirmed that the phosphorylation of LARS1 functions as the key molecular switch converting a nutrient signal into a cell growth signal.
The significance of this study lies in mapping, in concrete molecular detail, how cells sense amino acids and use that information to activate their growth switch. In particular, the study revealed that, upon receiving nutrient signals, the MSC—a complex involved in protein synthesis—releases its constituent protein LARS1, which then activates cellular growth signaling.
Some existing anticancer drugs work by directly inhibiting mTORC1, the cell's growth switch. However, because mTORC1 is also required for normal cellular growth and metabolism, its direct inhibition may also affect normal cells.
The research team expects that further identifying the kinase responsible for phosphorylating LARS1, along with its regulatory mechanism, could enable a more precise anticancer strategy—one that intercepts the growth signal further upstream, before it reaches mTORC1, rather than blocking mTORC1 itself.
The study was co-first-authored by Youjin Kim and Joo-Chan Kim from KAIST's Department of Chemistry and was published online in Nature Communications on June 11.
Paper title: Cryo-EM structure of the LARS1:IARS1 complex reveals a nutrient-responsive switch controlling mTORC1 signaling
DOI: https://doi.org/10.1038/s41467-026-74085-x
This work was supported by the National Research Foundation of Korea (grant nos. RS-2026-25482352 to H.S.P., RS-2024-00344154 to J.Y.K., and NRF-2021R1A3B1076605 to S.K.) and PNCC (grant no. 160183).
2026.07.27 View 895 -
KAIST Develops a Molecular Platform for the Selective Control of Oxygen Reaction Pathways
Controlling how oxygen reacts is important for improving technologies such as batteries, fuel cells, and environmentally sustainable chemical processes. A KAIST research team has developed a new molecular system that can selectively switch the pathway through which electrons are transferred during oxygen activation. The findings are expected to provide a fundamental design principle for next-generation catalysts and energy-conversion technologies.
KAIST (President Choongsik Bae) announced on the 22nd of July that a research team led by Professor Seung Jun Hwang from the Department of Chemistry has developed a molecular system capable of directing oxygen activation along a selected electron-transfer pathway. By combining germanium with a molecular framework that can store and transfer electrons, the team established a design principle for selectively switching oxygen activation between two- and four-electron pathways.
Catalysts for controlling oxygen reactions have traditionally been developed around transition-metal centers such as iron, cobalt, and nickel. Germanium, by contrast, is a main-group element in the same group of the periodic table as silicon and has generally been considered less suitable for reactions requiring the coordinated transfer of several electrons.
To overcome this limitation, the research team combined germanium with a redox-active ligand, a molecular framework capable of storing, accepting, and transferring electrons. The ligand serves as an electron reservoir and cooperates with the germanium center, allowing the entire molecular structure to participate in multielectron reactions.
When oxygen reacts, the products and reaction outcomes depend on whether two or four electrons are transferred. In general, two-electron oxygen reduction produces hydrogen peroxide, while four-electron reduction produces water. Selectively controlling these pathways is therefore an important challenge in the development of batteries, fuel cells, and greener chemical catalysts.
The study presents a rare example of a main-group molecular system in which two- and four-electron reactivity can be selectively accessed within the same underlying molecular framework. This approach broadens the range of elements that may be considered in catalyst design and provides an alternative strategy to relying exclusively on transition metals.
The team also succeeded in isolating and analyzing a germanium compound representing the two-electron stage of the reaction, which they stabilized by attaching a methyl group to the germanium complex. Remarkably, the germanium atom in this compound could both donate and accept electrons, providing an important clue to how the system controls different reaction pathways.
The team also confirmed the practical potential of the new system. Under mild, light-free conditions, the germanium complex removed halogen atoms such as bromine and chlorine from organic compounds and regenerated alkenes (organic compounds containing a carbon-carbon double bond), which are widely used as raw materials for pharmaceuticals, plastics, and other chemical products. These results suggest that useful chemical feedstocks could be produced through simpler and potentially more energy-efficient processes.
“We expect these findings to inform the development of next-generation catalysts for energy conversion and to contribute to more selective and efficient chemical processes.” said Professor Hwang.
The study was conducted by Sung Gyu Kim and Jinrok Oh, currently postdoctoral researchers in the KAIST Department of Chemistry, and Dae Eui Choi, a student in the combined master’s and doctoral program in the Department of Chemistry at POSTECH. The results were published online in the international journal Chem on July 6.
Paper title: Germanium Ligand Redox Cooperativity: A Key to Ambiphilicity and Switchable Two- and Four-Electron Transfer
DOI: 10.1016/j.chempr.2026.103127
This work was supported by National Research Foundation of Korea grants funded by the Korean government through the Ministry of Science and ICT (NRF-2021R1C1C1010220 and RS-2025-02216980), and by the Samsung Science and Technology Foundation under Project No. SSTF-BA2101-09. Sung Gyu Kim received research fellowship support from the Basic Science Research Program through the National Research Foundation of Korea, funded by the Ministry of Education (RS-2024-00415390).
2026.07.22 View 824 -
KAIST’s Solarstill Box Wins Red Dot’s Highest Honor for Producing Clean Water Using Only Sunlight
A KAIST design that produces clean drinking water using only sunlight, without electricity or fuel, has won one of the world’s most prestigious design awards. The design received high international recognition not only for its technical completeness, but also for its sustainable approach, which enables residents in regions affected by water scarcity and water pollution to produce and manage clean water on their own.
KAIST (President Choongsik Bae) announced on the 17th of July that “Solarstill Box,” a solar-powered water purification and desalination device developed by a research team led by Professor Sangmin Bae from the Department of Industrial Design, has won the “Red Dot: Best of the Best” award in the Social Impact category at the Red Dot Award: Design Concept 2026, a globally renowned design competition.
The Red Dot Design Award is considered one of the world’s three major design awards, along with Germany’s iF Design Award and the United States’ IDEA (International Design Excellence Awards). Among them, the “Best of the Best” is the highest distinction, awarded to works that demonstrate the greatest innovation and completeness in each category.
This award is significant because it goes beyond recognition of product design excellence. It represents international acknowledgment that design can help address the shared human challenge of clean water access and create sustainable social value.
Solarstill Box is a low-cost water purification and desalination device that converts seawater or water containing salt and pollutants into drinking water through solar distillation. It was developed for coastal areas, saline regions, and off-grid communities that rely on contaminated water sources. The device is designed to produce clean water using only solar energy, without electricity, fuel, or separate filters.
The stepped trays inside the device increase the surface area for evaporation, improving the efficiency of solar distillation. As evaporated water vapor condenses on the transparent cover, contaminants such as salt, heavy metals, and bacteria are naturally separated, allowing only clean water to be collected.
Solarstill Box is also made of flat components based on Plaveneer sheets, allowing it to be produced and transported in a flat-pack format. Anyone can assemble it locally in about 20 minutes, and maintenance costs are reduced because only damaged parts need to be replaced. Another key feature is that it moves beyond the one-time delivery of relief supplies and instead creates a sustainable drinking water system that local residents can install and manage themselves.
Solarstill Box was developed as part of the “SEED Project,” a social contribution design research project by ID+IM Design Lab, led by Professor Sangmin Bae of the Department of Industrial Design, in collaboration with World Vision. Following this award, the research team plans to work with World Vision to pursue product commercialization and establish local distribution models. In the long term, the team aims to expand the project into a cooperative-based operating model in which local residents directly participate in manufacturing, distribution, and maintenance, thereby supporting both clean water access and sustainable community development.
The project aimed to improve access to clean drinking water in low-resource regions where water scarcity and pollution make it difficult to secure safe water. The design development was carried out by Professor Sangmin Bae, doctoral student Jungwoo Kim, master’s student Minsu Kim, and undergraduate student Seunghee Han.
Professor Sangmin Bae said, “Design should go beyond creating beautiful products; it should serve as a tool for solving social problems and changing people’s lives,” adding, “We hope Solarstill Box will provide practical help to communities in need of clean water and spread as a sustainable drinking water system that residents can operate on their own.”
Solarstill Box will be introduced to a global audience through the official award ceremony and exhibition of the Red Dot Award: Design Concept 2026, which will be held in October.
2026.07.20 View 728 -
KAIST Study Finds Politically Salient Immigration Issues Can Lead to Higher Industrial Pollution
When immigration or refugee issues become heated political topics, nearby factories may end up releasing more toxic substances. Although the two phenomena may appear unrelated, a KAIST-led international research team has found that they are in fact connected through the government’s limited administrative and fiscal resources.
KAIST (President Choongsik Bae) announced on the 10th of July that a joint research team led by Professor Narae Lee from The School of Business and Technology Management at KAIST, in collaboration with Professor Heli Wang from Singapore Management University (SMU), analyzed immigration-related legislation and environmental data across the United States and found that when immigration becomes a central political agenda, government environmental oversight weakens and firms’ toxic chemical releases increase. The research team describes this phenomenon as “institutional crowding.”
Government administrative capacity and budgets are not unlimited. When a new political issue emerges, government attention and resources become concentrated in that area. In the process, enforcement in relatively less visible policy areas, such as environmental oversight, may weaken. Although the research team analyzed immigration as a case study, they explain that this phenomenon is not limited to a specific issue. Rather, it represents a general mechanism that can arise when political agendas compete for limited government resources.
The research team combined data from the U.S. Environmental Protection Agency’s Toxics Release Inventory (TRI) with immigration-related legislative data from U.S. states. By analyzing a total of 82,377 observations collected from 14,390 manufacturing facilities across the United States between 2010 and 2018, the team found that each additional immigration-related bill was associated with an average increase of about 1% in toxic chemical releases per manufacturing facility. This is equivalent to approximately 25 kilograms, or 56 pounds, of additional toxic emissions per facility.
The researchers found that this increase was not caused by a relaxation of environmental regulatory standards. Rather, it occurred because firms reduced costly efforts to cut pollution and treat toxic waste as government environmental oversight became relatively less effective.
This pattern was especially pronounced in states facing fiscal constraints. In states with high debt or heavy fiscal burdens, environmental oversight weakened further when political attention shifted to new issues.This suggests that when government budgets are tight, resources are more likely to be allocated first to politically urgent issues, while environmental monitoring may be pushed down the priority list.
Professor Narae Lee said, “This study does not argue that immigration causes environmental pollution. Rather, it shows that shifts in the political agenda item can weaken environmental oversight and thereby increase corporate pollution,” adding, “Even when limited government resources are concentrated on a particular issue, environmental oversight needs to be institutionally protected so that it remains stable.”
The study is significant in that it empirically identifies how competition among political agendas can affect firms’ environmental pollution management. It also offers new implications for public policy and for advancing environmental justice, so that the burden of environmental pollution does not fall disproportionately on socially vulnerable groups.
The research was published online on May 29 in the Journal of Management, a leading international journal in the field of management, with Professor Narae Lee as the first author.
An earlier version of the paper received the POSCO Corporate Citizenship Research Award, the Robert J. Litschert Award from the Academy of Management, and the Best Paper with Practical Implications Award from the Strategic Management Society, recognizing the excellence and practical significance of the research.
※ Paper title: There’s More Than Meets the Eye: Assessing the Impact of Immigrants on Firm Environmental Performance, DOI: https://doi.org/10.1177/01492063261442451
2026.07.10 View 977 -
KAIST Automates the Search for “Dream Semiconductor” 2D Semiconductors
The era of researchers manually searching for two-dimensional semiconductors, which are drawing attention as next-generation AI semiconductors, is coming to an end. KAIST researchers have automated semiconductor screening and device fabrication, analyzed thousands of devices, and revealed the relationship between thickness and performance that had long been difficult to identify. This achievement is expected to shift next-generation semiconductor research toward a data-driven approach and accelerate the commercialization of AI semiconductors and ultra-low-power semiconductors.
KAIST (President Choongsik Bae) announced on the 9th that a research team led by Professor Jimin Kwon of the School of Electrical Engineering and the Department of AI System has developed a technology that automatically identifies two-dimensional semiconductors from optical microscope images alone and connects the process to transistor fabrication, through joint research with UNIST, Hanbat National University, Hanyang University, and Washington University in St. Louis in the United States.
Two-dimensional semiconductors are ultrathin semiconductors only a few atomic layers thick. They are called “dream semiconductors” because they can enable smaller semiconductors that consume less electricity than conventional silicon semiconductors. Today’s silicon semiconductors are approaching physical limits, as continued miniaturization of circuits leads to greater power loss and heat generation. Two-dimensional semiconductors, which are attracting attention as next-generation materials to overcome these limits, are expected to be used in a wide range of future technologies, including AI semiconductors, smartphones, data centers, wearable devices, foldable or stretchable electronics, and ultra-small medical sensors.
However, in two-dimensional semiconductors made through solution processing, the position, size, and thickness of each small semiconductor flake all differ, requiring researchers to find the desired samples one by one under a microscope. They then had to manually design electrodes according to the identified positions, requiring substantial time and effort, and making it practically difficult to analyze thousands or more devices at once.
The research team used molybdenum disulfide (MoS₂), a representative two-dimensional semiconductor material. By using the fact that the RGB red, green, and blue brightness values seen under a microscope change depending on thickness, the team enabled a computer to automatically identify the desired semiconductor and automatically design the electrodes. Verification using atomic force microscopy (AFM) confirmed that even subtle thickness differences of three to eight layers could be accurately distinguished.
Through this approach, the team successfully selected suitable samples automatically from more than 120,000 semiconductor flakes and fabricated and analyzed 1,615 transistors.
The large-scale analysis also produced meaningful results. The team statistically clarified for the first time that as the semiconductor becomes thicker, current flows more easily, but the ability to switch electricity on and off actually decreases. This characteristic had been difficult to confirm previously because only a small number of samples could be analyzed, but the team revealed it through large-scale data.
The greatest significance of this study is that it did not simply automate the fabrication process, but transformed two-dimensional semiconductor research, which had relied on human experience, into data-driven research. Going forward, the technology is expected to enable researchers to fabricate and analyze more semiconductors more quickly, identify high-performance materials, and ultimately expand into research in which AI designs new semiconductors.
This study was conducted with Professor Jimin Kwon, Dr. Haksoon Jung, and Dr. Yongwoo Lee of KAIST as co-corresponding authors, and Sanghyun Lee of UNIST as the first author. The research results were published on April 3 in Advanced Functional Materials, a leading international journal in materials science, and were also selected as an Inside Back Cover article in the field of 2D Materials & Electronics.
※ Paper title: Statistically Resolving Thickness-Dependent Electrical Characteristics in Multilayer-MoS₂ Transistors, DOI: 10.1002/adfm.202532204
※ Author information: Professor Jimin Kwon (KAIST, corresponding author), Dr. Haksoon Jung (KAIST, corresponding author), Dr. Yongwoo Lee (KAIST, corresponding author), Sanghyun Lee (UNIST, first author), and participating researchers from partner institutions: Sumin Hong (UNIST), Minho Park (UNIST), Professor Seongju Kim (Hanbat National University), Professor Sang-Hoon Baek (Hanyang University), Professor Joonki Suh (KAIST), Seonguk Yang (KAIST), Professor Sang-Hoon Bae (Washington University in St. Louis), and Dr. Chang-Soo Lee (TDS)
This research was supported by the Individual Basic Research Program of the National Research Foundation of Korea (NRF), funded by the Ministry of Science and ICT (MSIT), and by the Advanced Strategic Industry Super-Gap Technology Development Program of the Korea Planning & Evaluation Institute of Industrial Technology (KEIT), funded by the Ministry of Trade, Industry and Energy (MOTIE).
2026.07.09 View 1272 -
KAIST Develops Core Display Technology That Prevents Image Distortion Even When Stretched
Beyond bendable and foldable displays, the era of stretchable displays, whose screens can expand freely like rubber, is now emerging. KAIST researchers have developed a core technology that allows text, images, and other on-screen information to retain their original shape even when the screen is stretched by up to 15%. The achievement is expected to help solve the problem of image distortion and accelerate the commercialization of next-generation high-quality stretchable displays.
KAIST (President Choongsik Bae) announced on the July 8 that a research team led by Professor Seunghyup Yoo of the School of Electrical Engineering, in collaboration with Professor Hanul Moon’s team at Dong-A University (President Hae Woo Lee), has successfully implemented an auxetic-based stretchable display platform. Auxetic structures expand in both width and length when pulled, allowing the display to stretch uniformly at the same ratio in all directions without distorting the image on the screen.
Conventional stretchable displays are generally made by forming light-emitting devices on a stretchable substrate, which serves as the base layer of the display. However, when such a substrate is stretched in one direction, it tends to shrink in the opposite direction, causing letters and images on the screen to become flattened or distorted. Auxetic structures have been used to address this problem, but most previous approaches were limited to maintaining the overall horizontal-to-vertical ratio of the screen, while the letters and images within the screen still remained vulnerable to distortion.
Instead of bonding the auxetic structure and the stretchable substrate across the entire surface, as in conventional methods, the research team proposed a new design approach that uses computational analysis to selectively connect only the necessary points that ensure isotropic expansion throughout the substrate.
In the conventional approach, the twisting deformation that occurs as the auxetic structure stretches is directly transferred to the substrate, distorting the image inside the screen. In contrast, the platform developed by the research team was designed so that each region moves evenly outward from its original position. This allows not only the entire screen but also small areas such as letters and images to expand together while maintaining their original shapes.
The research team verified the platform’s performance by repeatedly stretching a substrate patterned with letters and images in both the horizontal and vertical directions. In the conventional method, the patterns underwent local deformation, whereas in the new platform, the shapes of the letters and images remained intact. This demonstrates that not only the whole screen but also fine images on-screen can expand uniformly without distortion.
The team also integrated an LED array, a structure in which multiple LEDs are arranged at regular intervals, onto the platform to verify its performance as an working stretchable display. Even when stretched by up to 15% in both the horizontal and vertical directions, stable electrical operation and the screen brightness were maintained. After repeated stretching to 15%, the decrease in brightness remained below 2%, confirming the platform’s potential for practical display applications.
This technology is expected to serve as a core platform for next-generation electronics with freely changeable shapes, including wearable electronic devices, electronic skin, or e-skin, which refers to electronic devices that stretch like skin while sensing and displaying information, medical biosensors, soft robots, and curved displays for automobiles and aircraft.
Professor Seunghyup Yoo of KAIST said, “For stretchable displays to be used as actual information display devices, they must not only stretch well, but also preserve on-screen information accurately during stretching,” adding, “This platform enables uniform expansion from small areas of the screen to the entire display, and will serve as a key foundational technology for accelerating the commercialization of high-quality stretchable displays.”
This study was led by KAIST Dr. Su-Bon Kim and Dr. Junho Kim as co-first authors, with Professor Hanul Moon of Dong-A University and Professor Seunghyup Yoo of KAIST as co-corresponding authors. The research was published in the international journal Nature Communications on June 10.
※ Paper title: Hybrid auxetic metamaterial platforms enabling multiscale isotropic expansion for distortion-free stretchable displays, DOI: 10.1038/s41467-026-74141-6
This research was supported by the National Research Foundation of Korea (NRF) Mid-Career Researcher Program, the Future Display Strategic Research Laboratory Program, the Korea Planning & Evaluation Institute of Industrial Technology (KEIT), and the Korea Institute for Advancement of Technology (KIAT) HRD Program.
2026.07.08 View 1321